107 research outputs found
Weak gravity-like force detector by âAtom interferometersâ
A weak gravity-like force detector is proposed using a novel scheme, through which the
subtle modification of a weak gravity-like force on the interference pattern can be
obtained. The weak gravity-like force creates two spatially imbalanced Bose-Einstein
condensates (BECs) trapped in a symmetric double-well and makes a shift of the
interference fringes yielded after expansion of the BECs. The strength of the weak
gravity-like force is revealed by investigating the Loschmidt echo and it can be read out
by analysing the density profile of interference fringes. For the weak gravity-like force,
we predict that the sensitivity can be Ύg ~ 10-6
424 RELATIONSHIP OF ADIPOSITY TO INFLAMMATORY COMPONENTS OF KNEE OSTEOARTHRITIS (OA): THE MOST STUDY
Reliability of a uni-compartmental scale for the radiographic evaluation of knee arthritis: data from the multicenter osteoarthritis study
401 A NOVEL SEMIQUANTITATIVE WHOLE-KNEE SCORING SYSTEM FOR THE ASSESSMENT OF SYNOVITIS IN KNEE OA ON CONTRAST-ENHANCED MRI â THE MOST STUDY
Non-Peptidic Small Molecule Components from Cone Snail Venoms
Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (\u3e15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against predators and for competitive interactions were relatively small, structured peptides (10â35 amino acids), most with multiple disulfide crosslinks. These venom components (âconotoxins, conopeptidesâ) have been widely studied in many laboratories, leading to pharmaceutical agents and probes. In this review, we describe how it has recently become clear that to varying degrees, cone snail venoms also contain bioactive non-peptidic small molecule components. Since the initial discovery of genuanine as the first bioactive venom small molecule with an unprecedented structure, a broad set of cone snail venoms have been examined for non-peptidic bioactive components. In particular, a basal clade of cone snails (Stephanoconus) that prey on polychaetes produce genuanine and many other small molecules in their venoms, suggesting that this lineage may be a rich source of non-peptidic cone snail venom natural products. In contrast to standing dogma in the field that peptide and proteins are predominantly used for prey capture in cone snails, these small molecules also contribute to prey capture and push the molecular diversity of cone snails beyond peptides. The compounds so far characterized are active on neurons and thus may potentially serve as leads for neuronal diseases. Thus, in analogy to the incredible pharmacopeia resulting from studying venom peptides, these small molecules may provide a new resource of pharmacological agents
Coâfiring characteristics and kinetic analysis of distillersâ grains/coal for power plant
Joint detection and tracking algorithm for cognitive radar based on parallel structure of EKF and particle filter
Characterization and in-situ formation mechanism of tungsten carbide reinforced Fe-based alloy coating by plasma cladding
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