149 research outputs found
Quasi-one-dimensional antiferromagnetism and multiferroicity in CuCrO
The bulk magnetic properties of the new quasi-one-dimensional Heisenberg
antiferromagnet, CuCrO, were characterized by magnetic susceptibility, heat
capacity, optical spectroscopy, EPR and dielectric capacitance measurements and
density functional evaluations of the intra- and interchain spin exchange
interactions. We found type-II multiferroicity below the N\'{e}el temperature
of 8.2(5) K, arising from competing antiferromagnetic nearest-neighbor () and next-nearest-neighbor () intra-chain spin exchange
interactions. Experimental and theoretical results indicate that the ratio
is close to 2, putting CuCrO in the vicinity of
the Majumdar-Ghosh point.Comment: 9 pages, 8 figures, submitted to PR
IFRS, synchronicity, and financial crisis: the dynamics of accounting information for the Brazilian capital market
Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP
Undifferentiated rat pheochromocytoma (PC12) cells extend neurites when cultured in the presence of nerve growth factor (NGF). Extracellular guanosine synergistically enhances NGF-dependent neurite outgrowth. We investigated the mechanism by which guanosine enhances NGF-dependent neurite outgrowth. Guanosine administration to PC12 cells significantly increased guanosine 3-5-cyclic monophosphate (cGMP) within the first 24Â h whereas addition of soluble guanylate cyclase (sGC) inhibitors abolished guanosine-induced enhancement of NGF-dependent neurite outgrowth. sGC may be activated either by nitric oxide (NO) or by carbon monoxide (CO). \documentclass[12pt]{minimal}
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\end{document}-Nitro-l-arginine methyl ester (l-NAME), a non-isozyme selective inhibitor of nitric oxide synthase (NOS), had no effect on neurite outgrowth induced by guanosine. Neither nNOS (the constitutive isoform), nor iNOS (the inducible isoform) were expressed in undifferentiated PC12 cells, or under these treatment conditions. These data imply that NO does not mediate the neuritogenic effect of guanosine. Zinc protoporphyrin-IX, an inhibitor of heme oxygenase (HO), reduced guanosine-dependent neurite outgrowth but did not attenuate the effect of NGF. The addition of guanosine plus NGF significantly increased the expression of HO-1, the inducible isozyme of HO, after 12Â h. These data demonstrate that guanosine enhances NGF-dependent neurite outgrowth by first activating the constitutive isozyme HO-2, and then by inducing the expression of HO-1, the enzymes responsible for CO synthesis, thus stimulating sGC and increasing intracellular cGMP
Intended and Unintended Consequences of Mandatory IFRS Adoption: A Review of Extant Evidence and Suggestions for Future Research
Control of the phosphorylation of the astrocyte marker glial fibrillary acidic protein (GFAP) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity
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