4,260 research outputs found
Comparing the 5-year health state utility vale of cervical disc replacement and anterior cervical discectomy and fusion
Investigating the 7-year cost-effectiveness of single-level cervical disc replacement compared to anterior cervical discectomy and fusion
Willow on yellowstone's northern range: Evidence for a trophic cascade?
Reintroduction of wolves (Canis lupus) to Yellowstone National Park in 1995-1996 has been argued to promote a trophic cascade by altering elk (Cervus elaphus) density, habitat-selection patterns, and behavior that, in turn, could lead to changes within the plant communities used by elk. We sampled two species of willow (Salix boothii and S. geyeriana) on the northern winter range to determine whether (1) there was quantitative evidence of increased willow growth following wolf reintroduction, (2) browsing by elk affected willow growth, and (3) any increase in growth observed was greater than that expected by climatic and hydrological factors alone, thereby indicating a trophic cascade caused by wolves. Using stem sectioning techniques to quantify historical growth patterns we found an approximately twofold increase in stem growth-ring area following wolf reintroduction for both species of willow. This increase could not be explained by climate and hydrological factors alone; the presence of wolves on the landscape was a significant predictor of stem growth above and beyond these abiotic factors. Growth-ring area was positively correlated with the previous year's ring area and negatively correlated with the percentage of twigs browsed from the stem during the winter preceding growth, indicating that elk browse impeded stem growth. Our results are consistent with the hypothesis of a behaviorally mediated trophic cascade on Yellowstone's northern winter range following wolf reintroduction. We suggest that the community-altering effects of wolf restoration are an endorsement of ecological-process management in Yellowstone National Park
Construction of Parseval wavelets from redundant filter systems
We consider wavelets in L^2(R^d) which have generalized multiresolutions.
This means that the initial resolution subspace V_0 in L^2(R^d) is not singly
generated. As a result, the representation of the integer lattice Z^d
restricted to V_0 has a nontrivial multiplicity function. We show how the
corresponding analysis and synthesis for these wavelets can be understood in
terms of unitary-matrix-valued functions on a torus acting on a certain vector
bundle. Specifically, we show how the wavelet functions on R^d can be
constructed directly from the generalized wavelet filters.Comment: 34 pages, AMS-LaTeX ("amsproc" document class) v2 changes minor typos
in Sections 1 and 4, v3 adds a number of references on GMRA theory and
wavelet multiplicity analysis; v4 adds material on pages 2, 3, 5 and 10, and
two more reference
Osteopontin Expression during Early Cerebral Ischemia-Reperfusion in Rats: Enhanced Expression in the Right Cortex Is Suppressed by Acetaminophen
Osteopontin (OPN) is a pleiotropic protein implicated in various inflammatory responses including ischemia-reperfusion (I-R) injury. Two distinct forms of the protein have been identified: an extensively studied secreted form (sOPN) and a less-well-known intracellular form (iOPN). Studies have shown that increased OPN expression parallels the time course of macrophage infiltration into injured tissue, a late event in the development of cerebral infarcts. sOPN has been suggested to promote remodeling of the extracellular matrix in the brain; the function of iOPN may be to facilitate certain signal transduction processes. Here, we studied OPN expression in adult male Sprague-Dawley rats subjected to global forebrain I-R injury. We found iOPN in the cytoplasm of both cortices and the hippocampus, but unexpectedly only the right cortex exhibited a marked increase in the iOPN level after 45 min of reperfusion. Acetaminophen, a drug recently shown to decrease apoptotic incidence, caspase-9 activation, and mitochondrial dysfunction during global I-R, significantly inhibited the increase in iOPN protein in the right cortex, suggesting a role for iOPN in the response to I-R injury in the right cortex
Asymmetric polarity reversals, bimodal field distribution, and coherence resonance in a spherically symmetric mean-field dynamo model
Using a mean-field dynamo model with a spherically symmetric helical
turbulence parameter alpha which is dynamically quenched and disturbed by
additional noise, the basic features of geomagnetic polarity reversals are
shown to be generic consequences of the dynamo action in the vicinity of
exceptional points of the spectrum. This simple paradigmatic model yields long
periods of constant polarity which are interrupted by self-accelerating field
decays leading to asymmetric polarity reversals. It shows the recently
discovered bimodal field distribution, and it gives a natural explanation of
the correlation between polarity persistence time and field strength. In
addition, we find typical features of coherence resonance in the dependence of
the persistence time on the noise.Comment: 5 pages, 7 figure
<i>‘What retention’ means to me</i>: the position of the adult learner in student retention
Studies of student retention and progression overwhelmingly appear adopt definitions that place the institution, rather than the student, at the centre. Retention is most often conceived in terms of linear and continuous progress between institutionally identified start and end points.
This paper reports on research that considered data from 38 in-depth interviews conducted with individuals who had characteristics often associated with non-traditional engagement in higher education who between 2006 and 2010 had studied an ‘Introduction to HE’ module at one distance higher education institution, some of whom had progressed to further study at that institution, some of whom had not. The research deployed a life histories approach to seek a finer grained understanding of how individuals conceptualise their own learning journey and experience, in order to reflect on institutional conceptions of student retention.
The findings highlight potential anomalies hidden within institutional retention rates – large proportions of the interview participants who were not ‘retained’ by the institution reported successful progression to and in other learning institutions and environments, both formal and informal. Nearly all described positive perspectives on lifelong learning which were either engendered or improved by the learning undertaken. This attests to the complexity of individuals’ lives and provides clear evidence that institution-centric definitions of retention and progression are insufficient to create truly meaningful understanding of successful individual learning journeys and experiences. It is argued that only through careful consideration of the lived experience of students and a re-conception of measures of retention, will we be able to offer real insight into improving student retention
Utilitarian Collective Choice and Voting
In his seminal Social Choice and Individual Values, Kenneth Arrow stated that his theory applies to voting. Many voting theorists have been convinced that, on account of Arrow’s theorem, all voting methods must be seriously flawed. Arrow’s theory is strictly ordinal, the cardinal aggregation of preferences being explicitly rejected. In this paper I point out that all voting methods are cardinal and therefore outside the reach of Arrow’s result.
Parallel to Arrow’s ordinal approach, there evolved a consistent cardinal theory of collective choice. This theory, most prominently associated with the work of Harsanyi, continued the older utilitarian tradition in a more formal style. The purpose of this paper is to show that various derivations of utilitarian SWFs can also be used to derive utilitarian voting (UV). By this I mean a voting rule that allows the voter to score each alternative in accordance with a given scale. UV-k indicates a scale with k distinct values. The general theory leaves k to be determined on pragmatic grounds. A (1,0) scale gives approval voting. I prefer the scale (1,0,-1) and refer to the resulting voting rule as evaluative voting.
A conclusion of the paper is that the defects of conventional voting methods result not from Arrow’s theorem, but rather from restrictions imposed on voters’ expression of their preferences.
The analysis is extended to strategic voting, utilizing a novel set of assumptions regarding voter behavior
Mediating boundaries between knowledge and knowing: ICT and R4D praxis
Research for development (R4D) praxis (theory-informed practical action) can be underpinned by the use of Information and Communication Technologies (ICTs) which, it is claimed, provide opportunities for knowledge working and sharing. Such a framing implicitly or explicitly constructs a boundary around knowledge as reified, or commodified – or at least able to be stabilized for a period of time (first order knowledge). In contrast ‘third-generation knowledge’ emphasizes the social nature of learning and knowledge-making; this reframes knowledge as a negotiated social practice, thus constructing a different system boundary. This paper offers critical reflections on the use of a wiki as a data repository and mediating technical platform as part of innovating in R4D praxis. A sustainable social learning process was sought that fostered an emergent community of practice among biophysical and social researchers acting for the first time as R4D co-researchers. Over time the technologically mediated element of the learning system was judged to have failed. This inquiry asks: How can learning system design cultivate learning opportunities and respond to learning challenges in an online environment to support R4D practice? Confining critical reflection to the online learning experience alone ignores the wider context in which knowledge work took place; therefore the institutional setting is also considered
- …