Chiral-Odd and Spin-Dependent Quark Fragmentation Functions and their Applications

We define a number of quark fragmentation functions for spin-0, -1/2 and -1 hadrons, and classify them according to their twist, spin and chirality. As an example of their applications, we use them to analyze semi-inclusive deep-inelastic scattering on a transversely polarized nucleon.Comment: 19 pages in Plain TeX, MIT CTP #221

Electronic transport in a Cantor stub waveguide network

We investigate theoretically, the character of electronic eigenstates and transmission properties of a one dimensional array of stubs with Cantor geometry. Within the framework of real space re-normalization group (RSRG) and transfer matrix methods we analyze the resonant transmission and extended wave-functions in a Cantor array of stubs, which lack translational order. Apart from resonant states with high transmittance we unravel a whole family of wave-functions supported by such an array clamped between two-infinite ordered leads, which have an extended character in the RSRG scheme, but, for such states the transmission coefficient across the lead-sample-lead structure decays following a power-law as the system grows in size. This feature is explained from renormalization group ideas and may lead to the possibility of trapping of electronic, optical or acoustic waves in such hierarchical geometries

The box diagram in Yukawa theory

We present a light-front calculation of the box diagram in Yukawa theory. The covariant box diagram is finite for the case of spin-1/2 constituents exchanging spin-0 particles. In light-front dynamics, however, individual time-ordered diagrams are divergent. We analyze the corresponding light-front singularities and show the equivalence between the light-front and covariant results by taming the singularities.Comment: 21 pages, 17 figures. submittes to Phys. Rev.

Implications of Color Gauge Symmetry For Nucleon Spin Structure

We study the chromodynamical gauge symmetry in relation to the internal spin structure of the nucleon. We show that 1) even in the helicity eigenstates the gauge-dependent spin and orbital angular momentum operators do not have gauge-independent matrix element; 2) the evolution equations for the gluon spin take very different forms in the Feynman and axial gauges, but yield the same leading behavior in the asymptotic limit; 3) the complete evolution of the gauge-dependent orbital angular momenta appears intractable in the light-cone gauge. We define a new gluon orbital angular momentum distribution $L_g(x)$ which {\it is} an experimental observable and has a simple scale evolution. However, its physical interpretation makes sense only in the light-cone gauge just like the gluon helicity distribution $\Delta g(x)$y.Comment: Minor corrections are made in the tex

The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells

Escherichia coli’s heat-labile enterotoxin (Etx) and its non-toxic B subunit (EtxB) have been characterized as adjuvants capable of enhancing T cell responses to co-administered antigen. Here, we investigate the direct effect of intravenously administered EtxB on the size of the dendritic and mye-loid cell populations in spleen. EtxB treatment appears to enhance the development and turnover of dendritic and myeloid cells from precursors within the spleen. EtxB treatment also gives a dendritic cell (DC) population with higher viability and lower activation status based on the reduced expression of MHC-II, CD80 and CD86. In this respect, the in vivo effect of EtxB differs from that of the highly inflammatory mediator lipopolysaccharide. In in vi-tro bone marrow cultures, EtxB treatment was also found to enhance the development of DC from precursors dependent on Flt3L. In terms of the in vivo effect of EtxB on CD4 and CD8 T cell responses in mice, the interaction of EtxB directly with DC was demonstrated following conditional deple-tion of CD11c+ DC. In summary, all results are consistent with EtxB displaying adjuvant ability by enhancing the turnover of DC in spleen, leading to newly mature myeloid and DC in spleen, thereby increasing DC capacity to perform as antigen-presenting cells on encounter with T cells

Positivity Constraints for Spin-Dependent Parton Distributions

We derive new positivity constraints on the spin-dependent structure functions of the nucleon. These model independent results reduce conside\-rably their domain of allowed values, in particular for the chiral-odd parton distribution $h_1 (x)$.Comment: 8 pages,CPT-94/P.3059,LaTex,3 fig available on cpt.univ-mrs.fr directory pub/preprints/94/fundamental-interactions/94-P.305

Reaper is regulated by IAP-mediated ubiquitination

In most cases, apoptotic cell death culminates in the activation of the caspase family of cysteine proteases, leading to the orderly dismantling and elimination of the cell. The IAPs (inhibitors of apoptosis) comprise a family of proteins that oppose caspases and thus act to raise the apoptotic threshold. Disruption of IAP-mediated caspase inhibition has been shown to be an important activity for pro-apoptotic proteins in Drosophila (Reaper, HID, and Grim) and in mammalian cells (Smac/DIABLO and Omi/HtrA2). In addition, in the case of the fly, these proteins are able to stimulate the ubiquitination and degradation of IAPs by a mechanism involving the ubiquitin ligase activity of the IAP itself. In this report, we show that the Drosophila RHG proteins (Reaper, HID, and Grim) are themselves substrates for IAP-mediated ubiquitination. This ubiquitination of Reaper requires IAP ubiquitin-ligase activity and a stable interaction between Reaper and the IAP. Additionally, degradation of Reaper can be blocked by mutating its potential ubiquitination sites. Most importantly, we also show that regulation of Reaper by ubiquitination is a significant factor in determining its biological activity. These data demonstrate a novel function for IAPs and suggest that IAPs and Reaper-like proteins mutually control each other's abundance

An optical fibre dynamic instrumented palpation sensor for the characterisation of biological tissue

AbstractThe diagnosis of prostate cancer using invasive techniques (such as biopsy and blood tests for prostate-specific antigen) and non-invasive techniques (such as digital rectal examination and trans-rectal ultrasonography) may be enhanced by using an additional dynamic instrumented palpation approach to prostate tissue classification. A dynamically actuated membrane sensor/actuator has been developed that incorporates an optical fibre Fabry–Pérot interferometer to record the displacement of the membrane when it is pressed on to different tissue samples. The membrane sensor was tested on a silicon elastomer prostate model with enlarged and stiffer material on one side to simulate early stage prostate cancer. The interferometer measurement was found to have high dynamic range and accuracy, with a minimum displacement resolution of ±0.4μm over a 721μm measurement range. The dynamic response of the membrane sensor when applied to different tissue types changed depending on the stiffness of the tissue being measured. This demonstrates the feasibility of an optically tracked dynamic palpation technique for classifying tissue type based on the dynamic response of the sensor/actuator

Novel Quark Fragmentation Functions and the Nucleon's Transversity Distribution

We define twist-two and twist-three quark fragmentation functions in Quantum Chromodynamics (QCD) and study their physical implications. Using this formalism we show how the nucleon's transversity distribution can be measured in single pion inclusive electroproduction.Comment: 10 pages, uses PHYZZX macro package, 2 PostScript figures (added using FIGURES). MIT-CTP-215