42 research outputs found

    The 100 most cited articles investigating the radiological staging of oesophageal and junctional cancer: a bibliometric analysis

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    Objectives Accurate staging of oesophageal cancer (OC) is vital. Bibliometric analysis highlights key topics and publications that have shaped understanding of a subject. The 100 most cited articles investigating radiological staging of OC are identified. Methods The Thomas Reuters Web of Science database with search terms including “CT, PET, EUS, oesophageal and gastro-oesophageal junction cancer” was used to identify all English language, full-script articles. The 100 most cited articles were further analysed by topic, journal, author, year and institution. Results A total of 5,500 eligible papers were returned. The most cited paper was Flamen et al. (n = 306), investigating the utility of positron emission tomography (PET) for the staging of patients with potentially operable OC. The most common research topic was accuracy of staging investigations (n = 63). The article with the highest citation rate (38.00), defined as the number of citations divided by the number of complete years published, was Tixier et al. investigating PET texture analysis to predict treatment response to neo-adjuvant chemo-radiotherapy, cited 114 times since publication in 2011. Conclusion This bibliometric analysis has identified key publications regarded as important in radiological OC staging. Articles with the highest citation rates all investigated PET imaging, suggesting this modality could be the focus of future research

    Novel therapies in genitourinary cancer: an update

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    In recent years, new treatment for renal cell carcinoma (RCC) has been a spotlight in the field of cancer therapeutics. With several emerging agents branded as 'targeted therapy' now available, both medical oncologists and urologists are progressively more hopeful for better outcomes. The new remedies may provide patients with improved survival and at the same time less toxicity when compared to traditional cytotoxic agents. This article will center on current and emerging treatment strategies for advanced RCC and other GU malignancies with updates from 2008 annual ASCO meeting

    Impatto dell’emergenza COVID-19 sui volumi di attività della chirurgia protesica ortopedica in sette Regioni italiane. Versione del 17 marzo 2021

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    Per fronteggiare la pandemia da COVID-19 e soddisfare i nuovi bisogni di assistenza, a marzo 2020 le Regioni italiane hanno sospeso la chirurgia elettiva, alcune fino a oltre metà giugno. Ogni anno, in Italia, si effettuano circa 200.000 sostituzioni articolari, si può stimare quindi che a causa del lockdown oltre 50.000 pazienti abbiano visto rinviato il proprio intervento. Lo studio, a cui partecipano sette Regioni, si propone di monitorare con analisi periodiche i volumi della chirurgia protesica articolare a partire dal 2020 confrontandoli con quelli del 2018 e 2019. Il rapporto presenta i risultati delle analisi sui dati delle Schede di Dimissione Ospedaliera relative ai pazienti dimessi entro il 30/09/2020 e pone le basi per una più approfondita valutazione degli effetti della situazione di emergenza sui pazienti. Vengono brevemente descritte le strategie per la riorganizzazione adottate dalle Regioni partecipanti e riportate le esperienze di alcune strutture dal punto di vista dei chirurghi coinvolti. I risultati ottenuti possono costituire un utile riferimento per i diversi stakeholder per misurare le dinamiche di recupero dei ritardi conseguenti alla sospensione della chirurgia elettiva e comprendere gli effetti sulle liste d’attesa di eventuali ulteriori sospensioni.To meet new healthcare demand caused by the COVID-19 pandemics, in March 2020 Italian Regions suspended elective surgery, in some cases beyond mid-June. About 200,000 joint replacements are performed every year in Italy. It can therefore be estimated that due to the lockdown over 50,000 patients have had their surgery postponed. The study involved 7 Regions to monitor the volumes of arthroplasty operations in 2020 and compare them with data from 2018 and 2019. The report presents the results of the analysis of the Hospital Discharge data until 30/09/2020 and lays the foundations for a more in-depth assessment of the effects of the emergency on patients. Furthermore, it describes the strategies of reorganization adopted by the participating Regions, as well as the experiences of some facilities from the point of view of the surgeons involved. The results of this report might be a useful resource for stakeholders as they allow to measure the recovering of the delays resulted from the suspension of elective surgery and can help understanding the effects of any further suspensions on the waiting lists
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