8 research outputs found
High-pressure structural, elastic and electronic properties of the scintillator host material, KMgF_3
The high-pressure structural behaviour of the fluoroperovskite KMgF_3 is
investigated by theory and experiment. Density functional calculations were
performed within the local density approximation and the generalized gradient
approximation for exchange and correlation effects, as implemented within the
full-potential linear muffin-tin orbital method. In situ high-pressure powder
x-ray diffraction experiments were performed up to a maximum pressure of 40 GPa
using synchrotron radiation. We find that the cubic Pm\bar{3}m crystal symmetry
persists throughout the pressure range studied. The calculated ground state
properties -- the equilibrium lattice constant, bulk modulus and elastic
constants -- are in good agreement with experimental results. By analyzing the
ratio between the bulk and shear modulii, we conclude that KMgF_3 is brittle in
nature. Under ambient conditions, KMgF_3 is found to be an indirect gap
insulator with the gap increasing under pressure.Comment: 4 figure
ΠΠ»Π΅ΡΠΎΡΠ½ΡΠ΅ ΡΠ΅Ρ Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅ΡΡΠ°ΡΠΊΠΈ
The article analyzes the experience of cellular technology application in the treatment of retinal degenerative diseases. Experimental studies proved the ability of stem cells for self-renewal, migration, integration and subsequent differentiation into most types of retinal nerve cells, including photoreceptors. The article describes the experience of application and complications arising from the application of the following types of stem cells: retinal pigment epithelium cells, neural stem cells, mesenchymal stem cells, bone marrow cells, cord blood stem cells, induced pluripotent stem cells. Main mechanisms of cells action are discussed, namely replacement therapy and paracrine effect. The article marks the role of stem cells in the induction of angiogenesis, suppressing the local inflammatory response and apoptosis. In conclusion, the author describes the use of hematopoietic stem cells of human umbilical cord blood for restoring visual impairment in patients with normotensive glaucoma.Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½ ΠΎΠΏΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ Π² Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π΄Π΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅ΡΡΠ°ΡΠΊΠΈ. Π ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡΡ
Π΄ΠΎΠΊΠ°Π·Π°Π½Π° ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ ΠΊ ΡΠ°ΠΌΠΎΠΎΠ±Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ, ΠΌΠΈΠ³ΡΠ°ΡΠΈΠΈ, ΠΈΠ½ΡΠ΅Π³ΡΠ°ΡΠΈΠΈ ΠΈ ΠΏΠΎΡΠ»Π΅Π΄ΡΡΡΠ΅ΠΉ Π΄ΠΈΡ-ΡΠ΅ΡΠ΅Π½ΡΠΈΡΠΎΠ²ΠΊΠ΅ Π² Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ ΡΠΈΠΏΠΎΠ² Π½Π΅ΡΠ²Π½ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ ΡΠ΅ΡΡΠ°ΡΠΊΠΈ, Π²ΠΊΠ»ΡΡΠ°Ρ ΡΠΎΡΠΎΡΠ΅ΡΠ΅ΠΏΡΠΎΡΠ½ΡΠ΅. ΠΠΏΠΈΡΠ°Π½ ΠΎΠΏΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΈ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΡ, Π²ΠΎΠ·Π½ΠΈΠΊΠ°ΡΡΠΈΠ΅ ΠΏΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΡΠ»Π΅Π΄ΡΡΡΠΈΡ
Π²ΠΈΠ΄ΠΎΠ² ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ: ΠΊΠ»Π΅ΡΠΎΠΊ ΠΏΠΈΠ³ΠΌΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ ΡΠΏΠΈΡΠ΅Π»ΠΈΡ, Π½Π΅ΠΉΡΠΎΠ½Π°Π»ΡΠ½ΡΡ
ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ, ΠΌΠ΅Π·Π΅Π½Ρ
ΠΈΠΌΠ°Π»ΡΠ½ΡΡ
ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΠ΅ ΠΊΠ»Π΅ΡΠΎΠΊ, ΠΊΠ»Π΅ΡΠΎΠΊ ΠΊΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°, ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ ΠΏΡΠΏΠΎΠ²ΠΈΠ½Π½ΠΎΠΉ ΠΊΡΠΎΠ²ΠΈ, ΠΈΠ½Π΄ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠ»ΡΡΠΈΠΏΠΎΡΠ΅Π½ΡΠ½ΡΡ
ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ. ΠΠ±ΡΡΠΆΠ΄Π°ΡΡΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΡ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΊΠ»Π΅ΡΠΎΠΊ, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ: Π·Π°ΠΌΠ΅ΡΠ°ΡΡΠ°Ρ ΡΠ΅ΡΠ°ΠΏΠΈΡ ΠΈ ΠΏΠ°ΡΠ°ΠΊΡΠΈΠ½Π½ΡΠΉ ΡΡΡΠ΅ΠΊΡ. ΠΡΠΌΠ΅ΡΠ΅Π½Π° ΡΠΎΠ»Ρ ΡΡΠ²ΠΎΠ»ΠΎΠ²ΡΡ
ΠΊΠ»Π΅ΡΠΎΠΊ Π² ΠΈΠ½Π΄ΡΠΊΡΠΈΠΈ Π°Π½Π³ΠΈΠΎΠ³Π΅Π½Π΅Π·Π°, ΠΏΠΎΠ΄Π°Π²Π»Π΅Π½ΠΈΠΈ ΠΌΠ΅ΡΡΠ½ΠΎΠΉ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΈ Π°ΠΏΠΎΠΏΡΠΎΠ·Π°. Π Π·Π°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠΈ Π°Π²ΡΠΎΡΠ°ΠΌΠΈ ΠΎΠΏΠΈΡΡΠ²Π°Π΅ΡΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΈΠΊΠ° ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π³Π΅ΠΌΠΎΠΏΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΊΠ»Π΅ΡΠΎΠΊ ΠΏΡΠΏΠΎΠ²ΠΈΠ½Π½ΠΎΠΉ ΠΊΡΠΎΠ²ΠΈ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° Π΄Π»Ρ Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ Π·ΡΠ΅Π½ΠΈΡ ΠΏΡΠΈ Π½ΠΎΡΠΌΠΎΡΠ΅Π½Π·ΠΈΠ²Π½ΠΎΠΉ Π³Π»Π°ΡΠΊΠΎΠΌΠ΅