6 research outputs found

    Assessment of DNA damage by Micellar Electrokinetic Chromathography

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    A simple and inexpensive MEKC method, which is able to assess base damage within DNA samples, is illustrated. After heat-acid hydrolysis of the DNA samples, both the percentage of each canonical DNA base and the relative amount of un-canonical DNA bases can be measured. This method is useful for an evaluation of the integrity of PCR-templates used in several fields of investigatio

    Assessment of DNA Damage by Micellar Electrokinetic ChromatographyCapillary Electrophoresis of Biomolecules

    No full text
    A simple and inexpensive MEKC method, which is able to assess base damage within DNA samples, is illustrated. After heat-acid hydrolysis of the DNA samples, both the percentage of each canonical DNA base and the relative amount of uncanonical DNA bases can be measured. This method is useful for an evaluation of the integrity of PCR templates used in several fields of investigation

    Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

    No full text
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