1,218 research outputs found

    Mentoring School-Age Children: A Classification of Programs

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    The number of mentoring programs providing adult support to youth has increased dramatically in recent years. This report presents information on the characteristics of programs serving school-aged youth (K-12). We found that rather than simply replicating the traditional Big Brothers Big Sisters model, newer programs are emphasizing somewhat more instrumental goals and activities, as well as experimenting with different types of relationships (group, school-based, etc.). Most programs seem to have sufficient infrastructure to screen, train, and supervise their mentors adequately, but many de-emphasize the importance of developing long-term relationships

    Handbook on thermophysical properties of oxygen

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    Handbook has been compiled by Cryogenic Data Center of National Bureau of Standards. It covers thermodynamic functions, physical properties, and heat transfer data for oxygen. Handbook addresses primarily low temperature regime, but also includes some data above room temperature

    Female breast cancer in New South Wales, Australia, by country of birth: implications for health-service delivery.

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    Background NSW has a multicultural population with increasing migration from South East Asia, the Western Pacific and Eastern Mediterranean. Objective To compare cancer stage, treatment (first 12 months) and survival for 12 country of birth (COB) categories recorded on the population-based NSW Cancer Registry. Design Historic cohort study of invasive breast cancers diagnosed in 2003–2016. Patients Data for 48,909 women (18+ ages) analysed using linked cancer registry, hospital inpatient and Medicare and pharmaceutical benefits claims data. Measurement Comparisons by COB using multivariate logistic regression and proportional hazards regression with follow-up of vital status to April 30th, 2020. Results Compared with the Australia-born, women born in China, the Philippines, Vietnam and Lebanon were younger at diagnosis, whereas those from the United Kingdom, Germany, Italy and Greece were older. Women born in China, the Philippines, Vietnam, Greece and Italy lived in less advantaged areas. Adjusted analyses indicated that: (1) stage at diagnosis was less localised for women born in Germany, Greece, Italy and Lebanon; (2) a lower proportion reported comorbidity for those born in China, the Philippines and Vietnam; (3) surgery type varied, with mastectomy more likely for women born in China, the Philippines and Vietnam, and less likely for women born in Italy, Greece and Lebanon; (4) radiotherapy was more likely where breast conserving surgery was more common (Greece, Italy, and Lebanon) and the United Kingdom; and (5) systemic drug therapy was less common for women born in China and Germany. Five-year survival in NSW was high by international standards and increasing. Adjusted analyses indicate that, compared with the Australian born, survival from death from cancer at 5 years from diagnosis was higher for women born in China, the Philippines, Vietnam, Italy, the United Kingdom and Greece. Conclusions There is diversity by COB of stage, treatment and survival. Reasons for survival differences may include cultural factors and healthier migrant populations with lower comorbidity, and potentially, less complete death recording in Australia if some women return to their birth countries for treatment and end-of-life care. More research is needed to explore the cultural and clinical factors that health services need to accommodate

    Isochoric thermal conductivity of solid nitrogen

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    The isochoric thermal conductivity of solid nitrogen has been investigated on four samples of different densities in the temperature interval from 20 K to the onset of melting. In alfa-N2 the isochoric thermal conductivity exhibits a dependence weaker than 1/T; in beta-N2 it increases slightly with temperature. The experimental results are discussed within a model in which the heat is transported by low-frequency phonons or by "diffusive" modes above the mobility boundary. The growth of the thermal conductivity in beta-N2 is attributed to the decreasing "rotational" component of the total thermal resistance, which occurs as the rotational correlations between the neighboring molecules become weaker.Comment: Postscript 12 pages, 3 figures, 1 table. To be published in 200

    Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer

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    A microfluidic mixer is applied to study the kinetics of calmodulin conformational changes upon Ca2+ binding. The device facilitates rapid, uniform mixing by decoupling hydrodynamic focusing from diffusive mixing and accesses time scales of tens of microseconds. The mixer is used in conjunction with multiphoton microscopy to examine the fast Ca2+-induced transitions of acrylodan-labeled calmodulin. We find that the kinetic rates of the conformational changes in two homologous globular domains differ by more than an order of magnitude. The characteristic time constants are ≈490 μs for the transitions in the C-terminal domain and ≈20 ms for those in the N-terminal domain of the protein. We discuss possible mechanisms for the two distinct events and the biological role of the stable intermediate, half-saturated calmodulin

    D-mesons: In-medium effects at FAIR

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    The DD-meson spectral density at finite temperature is obtained within a self-consistent coupled-channel approach. For the bare meson-baryon interaction, a separable potential is taken, whose parameters are fixed by the position and width of the Λc(2593)\Lambda_c (2593) resonance. The quasiparticle peak stays close to the free DD-meson mass, indicating a small change in the effective mass for finite density and temperature. Furthermore, the spectral density develops a considerable width due to the coupled-channel structure. Our results indicate that the medium modifications for the DD-mesons in nucleus-nucleus collisions at FAIR (GSI) will be dominantly on the width and not, as previously expected, on the mass.Comment: 18 pages, 3 figures, revised version accepted for publication in Phys. Lett.
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