Water rights, conflict and policy: Proceedings of a workshop held in Kathmandu, Nepal, January 22-24, 1996

IrrigationIrrigation managementWater rightsWater lawConflictFarmers' associations

Influence of process variables on the properties of simvastatin self-emulsifying granules obtained through high shear wet granulation

Improvements of the oral bioavailability of lipophilic drugs can be obtained using lipidic formulations such as the self-emulsifying drug delivery systems. The high shear wet granulation (HSWG), using microemulsions as binder, is a viable process to produce self-emulsifying granules. However only few information are present in the literature on the effect of process variables on the properties of the granules obtained with these binders. Consequently, this article compares the effects of some relevant experimental variables (impeller speed and massing time) on thefinal technological and pharmaceutical properties of the granules produced using simple water, or alternatively, a microemulsion as binder and containing simvastatin (SV) as model drug. The effects of the variables were determined by evaluating the granule median diameter, their particle size distribution, roundness, disintegration time and dissolution rate of SV. Results clearly demonstrated that the microemulsion-based process was less sensitive tooperating conditions than the water-based process. With microemulsion the nucleation process and growth regimes were more difficult to control, resulting in products with broader PSDs. At the same operatingconditions microemulsion-based granules were more brittle but rounder and showed smaller median diameter compared to water-based granules. The dissolution rate of simvastatin was not significantly affected by the operating conditions

Het aanspreken van klanten op verplichtingen.

__Abstract__ Dit onderzoek heeft als doel bij te dragen aan het vermogen en de motivatie van professionals in de sociale zekerheid om klanten op adequate wijze aan te spre

Innovative human resource management

__Purpose__ – External factors such as global competition and new technologies, require organizations to be innovative. Such organizational innovations also ask for innovative human resource management (HRM). However, in the current literature, it is not completely clear what innovative HRM means, as it is conceptualized in different ways. This study aims to provide clarity about innovative HRM by suggesting a new measurement scale; formulating hypotheses about some core determinants of innovative HRM; and investigating how innovative HRM relates to organizational innovation. __Design/methodology/approach__ – Using a sample of 719 Dutch organizations it was possible to investigate the properties of the inventory and examining several determinants of innovative HRM and how it relates to organizational innovation. __Findings__ – The innovative HRM scale is internally consistent and differs from other HRM indicators. It is explained by external developments, organizational size and stability of the organization. Finally, innovative HRM is a predictor of organizational innovation. __Originality/value__ – The measure that was developed in this paper is new to the literature. Innovative HRM has not beenmeasured in a similar way to date. Besides that, the innovative HRM Survey is a novel data set

Activation is not a panacea: active labour market policy, long-term unemployment and institutional complementarity

Evaluation studies of active labour market policy show different activation measures generate contradictory results. In the present study, we argue that these contradictory results are due to the fact that the outcomes of activation measures depend on other institutions. The outcome measure in this study is the long-term unemployment rate. Two labour market institutions are of special interest in this context: namely, employment protection and unemployment benefits. Both institutions, depending on their design, may either increase or decrease the effectiveness of active labour market policies in lowering long-term unemployment. Based on an analysis of macro-level data o

Secundaire arbeidsvoorwaarden en geluk

Hoe verhouden secundaire arbeidsvoorwaarden zich tot geluk? Om deze vraag te be-antwoorden is gebruik gemaakt van de Loonwijzer-webenquête (n=14.304). Uit deanalyse blijkt dat een secundaire arbeidsvoorwaarde, na gecontroleerd te zijn voor primaire arbeidsvoorwaarden, alleen voor de laptop/pc- thuisregeling en voor trainingeen positief verband met geluk laten zien. Secundaire arbeidsvoorwaarden in gesommeerde vorm hebben alleen een positief effect op geluk wanneer de toenameabsoluut is, maar niet wanneer de toename relatief is ten opzichte van anderen

Understanding Active Labour Market Policies : an institutional perspective on intended and unintended consequences

This dissertation studies active labour market policies from an institutional perspective to add to the current theoretical insights that stem primarily from rational choice theories. The first section of the dissertation focuses on how employment protection and unemployment benefits might be complementary with active labour market policies and how these complementarities might vary based on the economic growth level. The second part of the dissertation studies how active labour market policies are related to the unemployment risk and active learning attitude of people with various educational backgrounds

The Fossil Phase in the Life of a Galaxy Group

We investigate the origin and evolution of fossil groups in a concordance LCDM cosmological simulation. We consider haloes with masses between (1-5)\times10^{13} \hMsun and study the physical mechanisms that lead to the formation of the large gap in magnitude between the brightest and the second most bright group member, which is typical for these fossil systems. Fossil groups are found to have high dark matter concentrations, which we can relate to their early formation time. The large magnitude-gaps arise after the groups have build up half of their final mass, due to merging of massive group members. We show that the existence of fossil systems is primarily driven by the relatively early infall of massive satellites, and that we do not find a strong environmental dependence for these systems. In addition, we find tentative evidence for fossil group satellites falling in on orbits with typically lower angular momentum, which might lead to a more efficient merger onto the host. We find a population of groups at higher redshifts that go through a ``fossil phase'': a stage where they show a large magnitude-gap, which is terminated by renewed infall from their environment.Comment: 9 pages and 8 figures, submitted to MNRA