VueBox® for quantitative analysis of contrast-enhanced ultrasound in liver tumors1

Dynamic contrast-enhanced ultrasound (DCE-US) enables quantification of tumor perfusion. VueBox (R) is a platform independent external software using DICOM cine loops which objectively provides various DCE-US parameters of tumor vascularity. This review summaries its use for diagnosis and treatment monitoring of liver tumors. The existing literature provides evidence on the successful application of Vuebox (R) based DCE-US for characterization and differential diagnosis of focal liver lesions, as well as on its use for monitoring of local ablative therapies and of modern systemic treatment in oncology

REACTIVE OXYGEN SPECIES АND ANTIOXIDANT SYSTEM ОF PLANTS

Under the influence of adverse conditions reactive oxygen species (ROS) are formed, which lead to oxidative stress. Increasing the ROS content in plants can pose a threat to the cells, causing lipid peroxidation, oxidative damage to proteins, nucleic acids, as well as inhibition of enzymes, activation of the pathway of programmed cell death, and ultimately leading to cell death. Plants have a well developed defense system to counteract active forms of oxygen (ROS), including both limiting the formation of ROS and neutralizing them. Under normal conditions, the formation and degradation of the ROS are in equilibrium. At the same time, under stress, the antioxidant system can not cope with its task