4 research outputs found
The SCO4117 ECF sigma factor pleiotropically controls secondary metabolism and morphogenesis in streptomyces coelicolor
Quantitative proteome and phosphoproteome analyses of streptomyces coelicolor reveal proteins and phosphoproteins modulating differentiation and secondary metabolism
Pre-sporulation stages of Streptomyces differentiation:State-of-the-Art and Future Perspectives
Streptomycetes comprise very important industrial bacteria, producing twothirds of all clinically relevant secondary metabolites. They are mycelial microorganisms with complex developmental cycles that include programmed cell death (PCD) and sporulation. Industrial fermentations are usually performed in liquid cultures (large bioreactors), conditions in which Streptomyces strains generally do not sporulate, and it was traditionally assumed that there was no differentiation. In this work, we review the current knowledge on Streptomyces pre-sporulation stages of Streptomyces differentiation