Imaging Depths of Near-Infrared Quantum Dots in First and Second Optical Windows

Potential advantages of quantum dot (QD) imaging in the second optical window (SOW) at 1,000 to 1,400 nm over the first optical window (FOW) at 700 to 900 nm have attracted much interest. QDs that emit at 800 nm (800QDs) and QDs that emit at 1,300 nm (1,300QDs) are used to investigate the imaging depths at the FOW and SOW. QD images in biologic tissues are processed binarized via global thresholding method, and the imaging depths are determined using the criteria of contrast to noise ratio and relative apparent size. Owing to the reduced scattering in the SOW, imaging depth in skin can be extended by approximately three times for 1,300QD/SOW over 800QD/FOW. In liver, excitation of 1,300QD/SOW can be shifted to longer wavelengths; thus, the imaging depth can be extended by 1.4 times. Effects of quantum yield (QY), concentration, incidence angle, polarization, and fluence rate F on imaging depth are comprehensively studied. Under F approved by the Food and Drug Administration, 1,300QDs with 50% QY can reach imaging depths of 29.7 mm in liver and 17.5 mm in skin. A time-gated excitation using 1,000 times higher F pulses can obtain the imaging depth of ≈ 5 cm. To validate our estimates, in vivo whole-body imaging experiments are performed using small-animal models

Development of KSTAR in-vessel components and heating systems

In-vessel components of the Korea Superconducting Tokamak Advanced Research (KSTAR) were developed for 2010 campaign to provide a crucial circumstance for achieving the strongly shaped and diverted plasma. Moreover, the in-vessel components such as limiter, divertor, passive stabilizer, in-vessel control coil (IVCC) system demonstrated good performances satisfying the original design concepts. In addition to the plasma facing components and the IVCC, in-vessel cryo-pump (IVCP) system was also installed to leverage divertor operation. Besides the in-vessel components, there have been substantial progresses in development of the heating and current drive system. The KSTAR heating and current drive system includes all kinds of the major heating systems such as neutral beam injection (NBI), ion cyclotron range of frequency (ICRF), electron cyclotron resonance heating and current drive (ECH and ECCD), lower hybrid current drive (LHCD) systems. As an initial stage for full equipment of the heating systems to total power of 26 MW, several key systems such as 1st NBI (called NBI-1). ICRF, and ECH-assisted startup system successfully demonstrated their excellent feasibilities in the design and performances for dedication to the 2010 campaign. (C) 2011 Elsevier B.V. All rights reserved.X1178sciescopu