Palatal tremor after lithium and carbamazepine use: a case report

<p>Abstract</p> <p>Introduction</p> <p>Palatal tremor, characterized by rhythmic contractions of the soft palate, can occur secondary to pathology in the dentato-rubro-olivary pathway, or in the absence of such structural lesions. Its pathogenesis is only partially understood. We describe a case of probable drug-induced palatal tremor.</p> <p>Case presentation</p> <p>A 27-year-old Indian man had taken carbamazepine and lithium for 7 years for the treatment of a manic episode. He presented with a one-year history of bilateral rhythmic oscillations of his soft palate and tremors of his tongue. There were no other abnormalities detected from his examination or after detailed investigation.</p> <p>Conclusion</p> <p>Palatal tremors may result from medication used in the treatment of psychiatric disorders.</p

Production of Pectinase from Bacillus sonorensis MPTD1

U radu je ispitanaproizvodnja pektinaze na podlozi s agarom s pomoću sedam sojeva bakterija izoliranih iz pokvarenog voća i povrća. Najučinkovitiji soj, MPTD1, identificiran je kao soj bakterije Bacillus sonorensis. Primjenom Plackett-Burman i Box-Behnken statističkih planova optimirani su različiti parametri, te je utvrđeno da udjeliekstrakta kvasca, K2HPO4,NaNO3i KCl te vrijeme inkubacije negativno utječu na proizvodnju pektinaze. Najveća postignuta aktivnost enzima bila je 2,43 (μM/mL)/min. U ovom je radu po prvi put opisana proizvodnja pektinaze s pomoću bakterije Bacillus sonorensis.Seven isolates from spoiled fruits and vegetables were screened for pectinase produc¬tion using pectin agar plates and the most efficient bacterial strain, MPTD1, was identified as Bacillus sonorensis. Optimisation of various process parameters was done using Plack¬ett-Burman and Box-Behnken designs and it was found that parameters like yeast extract, K2HPO4, incubation time, NaNO3 and KCl have a negative impact on pectinase production. Parameters like pH and MgSO4 and pectin mass fractions have a positive impact on pecti¬nase production. The maximum obtained enzyme activity was 2.43 (μM/mL)/min. This is the first report on pectinase production by Bacillus sonorensis

Diagnostic formulation

Writing a ‘Diagnostic Formulation’ is a skill expected of candidates in the post-graduate examinations in psychiatry in most universities in India. However there is ambiguity regarding what the term means and how it should be written. This article is an attempt to provide some guidelines on this topic

Situational psychogenic anejaculation: A case study

Anejaculation is an uncommon clinical entity that may result from a variety of causes, both organic and psychological. Psychogenic anejaculation is influenced by relationship, behavioral, and psychological factors. We present a clinical case of situational anejaculation, which was managed with a combination of techniques that addressed these factors including changes in masturbatory technique, improved marital communication and quality, and reduction of anxiety using cognitive behavioral techniques. It is suggested that the standard techniques of sex therapy be modified and tailored to manage the specific problems of the individual patient

The clinical pattern of diarrhoeal illness caused by the new epidemic variant of non-O1 Vibrio cholerae

This article does not have an abstract

Cariprazine Augmentation in Inadequate Clozapine Response: A Case Series

Managing patients with treatment-resistant schizophrenia who do not respond adequately to Clozapine poses a challenge. Cariprazine, with its unique mechanism of action, may be an option for such patients. The additional benefits of using Cariprazine as an augmentation strategy include once-daily dosing, ease of titration, and a favourable side-effect profile. The report outlines the experience of six patients with treatment-resistant schizophrenia who did not respond to Clozapine. The addition of Cariprazine was tolerated by all the patients. The majority showed improvement with symptom reduction, and in some cases, the dose of Clozapine could be reduced, thereby decreasing the side-effects of Clozapine