Lymphadenopathies: An Annoyance or Not?

Aim:The aim of this study was to evaluate the cases hospitalized with lymphadenopathy in terms of demographic and clinical characteristics, lymph node involvement regions, infection markers and their diagnoses.Materials and Methods:The medical records of 56 children with lymphadenopathy between 2014 and 2017 were reviewed retrospectively at Ege University, Children’s Hospital, General Pediatrics Unit. Demographic characteristics, clinical findings and accompanying complaints of the cases were examined. Laboratory tests including complete blood count, sedimentation rates and other biochemical parameters were measured. Lymph nodes were assessed via ultrasonographic examination in terms of distribution, number, size and structure. Lymph node regions were described as anterior or posterior cervical, supraclavicular, submandibular, axillary, epitrochlear, inguinal or popliteal. Laboratory results, microbiological studies and histopathological examination results of the patients were evaluated.Results:Among the 56 patients enrolled in the study, 31 (55.4%) were male, 25 (44.6%) were female and the median age was 3.7±7.1 years. The most frequent involvement location of the enlarged lymph nodes was the cervical area. Others occurred in the axillary, inguinal or supraclavicular regions. The median results of the white blood cell, C-reactive protein and erythrocyte sedimentation rates were 13.670±9760/mm3, 1.9±5.4 mg/dL and 42±51 mm/h respectively. Ultrasonographic evaluation showed that lymph nodes were diagnosed with reactive hyperplasia in 69.6%, suppurative lymphadenopathy in 23.2% and suspected malignancy in 7.1%. Most of the cases with lymphadenopathy resulted from a benign condition.Conclusion:Lymphadenopathy is a common complaint of childhood, mostly benign. The etiology should be elucidated using full history, careful physical examination, follow-up, laboratory and imaging methods. A good physical examination and follow-up of the clinical features of the lymph node are more important than the laboratory and imaging methods. If there is no change in lymph node size in the follow-up, further studies should be performed

Seasonal Variation of Vitamin D via Several Parameters in Adolescents

Aim:Vitamin D in adolescents reveals that subclinical vitamin D deficiency is continuously increasing worldwide. The aim of this study was to investigate the prevalence of vitamin D and subclinical vitamin D deficiency and risk factors among adolescents in the summer and winter seasons in İzmir.Materials and Methods:The medical records of 90 adolescents were reviewed regarding their vitamin D status in the summer and winter seasons. Blood samples were obtained from 90 adolescents at the end of summer and the end of winter. These samples were assessed for calcium (Ca++), phosphorus, magnesium (Mg), parathyroid hormone, alkaline phosphatase and 25-hydroxyvitamin D concentrations. The subjects were divided into two groups; the first group consisted of the patients who were assessed for vitamin D levels and the other laboratory measurements at the end of winter (n=46), the second group consisted of the patients who were assessed for the same laboratory features at the end of summer (n=44). The two groups were compared in terms of demographic, clinical and laboratory characteristics.Results:Among the 90 patients enrolled in the study, 41 (45.5%) were males and 49 (54.5%) were females. The median age was 11±4 years. Vitamin D deficiency percentages of the study group for the end of the winter period was 60.8% and for the end of the summer period was 6.8% but this was not statistically significant. Vitamin D insufficiency percentages of the winter group were higher than the summer group (93.2% vs. 39.2%, p>0.05). There were no differences between the groups in terms of laboratory findings concerning Ca, Mg and the other bone parameters.Conclusion:Contrary to the expected, we did not detect a seasonal difference in vitamin D levels in adolescents. Although laboratory findings were not found to be statistically significant in terms of vitamin D levels, we can state that the level of vitamin D in the winter season might be lower than the summer season. Therefore, it should be kept in mind that vitamin D insufficiency is more frequent at the end of the winter season and seasonal differences in the adolescent population should be considered during measurement

Diagnostic Value of the Mean Platelet Volume in the Prediction of Respiratory Syncytial Virus in Acute Bronchiolitis

Aim:Respiratory syncytial virus (RSV) is a viral pathogen that causes lower respiratory system infections in childhood. The purpose of this study was to examine whether mean platelet volume (MPV) changes are significant in the prediction of RSV bronchiolitis.Materials and Methods:One hundred and eighty-four infants who were diagnosed with acute bronchiolitis were divided into groups based on being RSV positive and other respiratory viruses positive. Using the receiver operating characteristic (ROC), diagnostic accuracy was evaluated according to the areas under the curves (AUC) for the diagnosis of bronchiolitis. A p value of 0.05) and other viruses. ROC curve analysis indicates that the MPV level cut-off point for making the diagnosis of single RSV bronchiolitis was 6.63 fL with a sensitivity and specificity of 55% and 63% respectively. The median AUC was 0.384 for the MPV (95% CI 0.270-0.499, p=0.04).Conclusion:Volume of MP may be a useful marker to provide a prediction on single RSV bronchiolitis. However, the measurement of MPV might not be correct and sufficient to provide a prediction on the types of respiratory viruses in bronchiolitis

Çocuklarda, astma bronşiale kriz sağıltımında, adrenalin efedrin kürü ile terbutalin inhalasyonunun karşılaştırılması

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.Çocukluk yaşlarında A"Bronchiale kriz sağıltımmda genellikle uygulanan adrenalin efedrin kürü ile elde edilen iyileşmeyi, selektir betao agonisti olan terbutalin inhalas- yonuyla elde edilenle karşılaştırma amacıyla, Ege Üniversite si Eg