HISTOFUNCTION TRANSFORMATION IN ENDOCRINE AND IMMUNE ORGANS UNDER VARIOUS REGIMEN INFLUENCE OF ELECTROMAGNETIC RADIATION

The effects of resonance and no-resonance of the low-intensify EMW frequency regimes were examined in Vistar rats,males. The microscopic structures and histochemical changes in thyroid, thymus,adrenals,ovaries,and other organs were studied. Our researchers evidenced, that the resonance EMW frequency regime slightly stimulates cell mitotic activity and exchange of substances in organ’s parenchyma and micro-circulation in connective tissue stroma. Treatment the course of no-resonance frequency EMW regime deteriorates the ratio between parenchyma and mesenchyme components correlation is detected in organ

Peculiarities of microcirculatory reactions after subcutaneous implantation of polycaprolactone matrices mineralized by vaterite

The aim is to assess skin microcirculation changes arising during subcutaneous implantation of polycaprolactone scaffolds mineralized by vaterite. Material and Methods. The experiment was carried out on 30 albino rats divided into two groups: a negative control group and an experimental one. We implanted polycaprolactone scaffold with exhausted foreign protein subcutaneously into rats of the negative control group. We implanted polycaprolactone matrix mineralized by vaterite subcutaneously into the animals of the experimental group. Research methods include laser Doppler flowmetry and morphological examination of the tissues of the matrix implantation area. Results. Changes of skin microcirculation over the matrix allocation area correspond to the morphological pattern of tissue reactions. Biocompat-ibility disorders take the form of inflammation in the scaffold implantation area that is accompanied by stable perfusion rise associated with local bloodstream modulation changes. We did not observe inflammation signs in the surrounding scaffold tissues during implantation of polycaprolactone matrices mineralized by vaterite. Besides local microcircula-tory reactions possess a transient character disappearing completely by the 21st day after the implantation. Conclusion. Complex of the given functional and morphological studies allow us to ascertain high-grade biocompatibility of polycaprolactone matrices mineralized by vaterite thus giving rise to prospect of their use for tissue regeneration stimulation.</p