Quantitative Structure-Activity Relationship Modeling and Bayesian Networks: Optimality of Naive Bayes Model

Previously, computational drag design was usually based on simplified laws of molecular physics, used for calculation of ligand’s interaction with an active site of a protein-enzyme. However, currently, this interaction is widely estimated using some statistical properties of known ligand-protein complex properties. Such statistical properties are described by quantitative structure-activity relationships (QSAR). Bayesian networks can help us to evaluate stability of a ligand-protein complex using found statistics. Moreover, we are possible to prove optimality of Naive Bayes model that makes these evaluations simple and easy for practical realization. We prove here optimality of Naive Bayes model using as an illustration ligand-protein interaction

Vision-Based Navigation III: Pose and Motion from Omnidirectional Optical Flow and a Digital Terrain Map

An algorithm for pose and motion estimation using corresponding features in omnidirectional images and a digital terrain map is proposed. In previous paper, such algorithm for regular camera was considered. Using a Digital Terrain (or Digital Elevation) Map (DTM/DEM) as a global reference enables recovering the absolute position and orientation of the camera. In order to do this, the DTM is used to formulate a constraint between corresponding features in two consecutive frames. In this paper, these constraints are extended to handle non-central projection, as is the case with many omnidirectional systems. The utilization of omnidirectional data is shown to improve the robustness and accuracy of the navigation algorithm. The feasibility of this algorithm is established through lab experimentation with two kinds of omnidirectional acquisition systems. The first one is polydioptric cameras while the second is catadioptric camera.Comment: 6 pages, 9 figure