Parameter Estimation of Stellar Mass Binary Black Holes under the Network of TianQin and LISA

We present a Bayesian parameter estimation progress to infer the stellar mass binary black hole properties by TianQin, LISA, and TianQin+LISA. Two typical Stellar-mass Black Hole Binary systems, GW150914 and GW190521 are chosen as the fiducial sources. In this work, we establish the ability of TianQin to infer the parameters of those systems and first apply the full frequency response in TianQin's data analysis. We obtain the parameter estimation results and explain the correlation between them. We also find the TianQin+LISA could marginally increase the parameter estimation precision and narrow the $1\sigma$ area compared with TianQin and LISA individual observations. We finally demonstrate the importance of considering the effect of spin when the binaries have a non-zero component spin and great derivation will appear especially on mass, coalescence time and sky location.Comment: 17 pages, 6 figures, comments welcom

Diagnosis and surgical treatment of multiple endocrine neoplasia type 2A

BACKGROUND: This study aims to introduce the diagnosis and surgical treatment of the rare disease multiple endocrine neoplasia type 2A (MEN 2A). METHODS: Thirteen cases of MEN 2A were diagnosed as medullary thyroid carcinoma (MTC) and pheochromocytoma by biochemical tests and imaging examination. They were treated by bilateral adrenal tumor excision or laparoscopic surgery. RESULTS: Nine patients were treated by bilateral adrenal tumor excision and the remaining four were treated by laparoscopic surgery for pheochromocytoma. Ten patients were treated by total thyroidectomy and bilateral lymph nodes dissection and the remaining three were treated by unilateral thyroidectomy for MTC. Up to now, three patients have died of MTC distant metastasis. CONCLUSIONS: We confirmed that MEN 2A can be diagnosed by biochemical tests and imaging examination when genetic testing is not available. Surgical excision is the predominant way to treat MEN 2A; pheochromocytoma should be excised at first when pheochromocytoma and MTC occur simultaneously

Near Real-Time Gravitational Wave Data Analysis of the Massive Black Hole Binary with TianQin

Space-borne gravitational wave detectors can detect sources like the merger of massive black holes. The rapid identification and localization of the source would play a crucial role in multi-messenger observation. The geocentric orbit of the space-borne gravitational wave detector, TianQin, makes it possible to conduct real-time data transmission. In this manuscript, we develop a search and localization pipeline for massive black hole binaries with TianQin, under both regular and real-time data transmission modes. We demonstrate that with real-time data transmission, it is possible to accurately localize the massive black hole binaries on-the-fly. With the approaching of the merger, the localization rapidly shrinks, and the data analysis can be finished at a speed comparable to the data downlink speed

Measuring the Hubble Constant Using Strongly Lensed Gravitational Wave Signals

The measurement of the Hubble constant $H_0$ plays an important role in the study of cosmology. In this letter, we propose a new method to constrain the Hubble constant using the strongly lensed gravitational wave (GW) signals. By reparameterizing the waveform, we find that the lensed waveform is sensitive to the $H_0$. Assuming the scenario that no electromagnetic counterpart of the GW source can be identified, our method can still give meaningful constraints on the $H_0$ with the information of the lens redshift. We then apply Fisher information matrix and Markov Chain Monte Carlo to evaluate the potential of this method. For the space-based GW detector, TianQin, the $H_0$ can be constrained within a relative error of $\sim$ 0.3-2\%, using a single strongly lensed GW event. Precision varies according to different levels of electromagnetic information.Comment: 8 pages, 4 figure

Impact of combinations of time-delay interferometry channels on stochastic gravitational wave background detection

The method of time delay interferometry (TDI) is proposed to cancel the laser noise in space-borne gravitational-wave detectors. Among all different TDI combinations, the most commonly used ones are the orthogonal channels A, E and T, where A and E are signal-sensitive and T is signal-insensitive. Meanwhile, for the detection of stochastic gravitational-wave background, one needs to introduce the overlap reduction function to characterize the correlation between channels. For the calculation of overlap reduction function, it is often convenient to work in the low-frequency approximation, and assuming the equal-arm Michelson channels. However, if one wishes to work on the overlap reduction function of $\rm A/E$ channels, then the low-frequency approximation fails. We derive the exact form of overlap reduction function for $\rm A/E$ channels. Based on the overlap reduction function, we calculate the sensitivity curves of TianQin, TianQin I+II and TianQin + LISA. We conclude that the detection sensitivity calculated with $\rm A/E$ channels is mostly consistent with that obtained from the equal-arm Michelson channels.Comment: 18 pages,10 figure

Hydrocarbon Detection Based on Phase Decomposition in Chaoshan Depression, Northern South China Sea

Located in the northern South China Sea, Chaoshan Depression is mainly a residual Mesozoic depression, with a construction of Meso-Cenozoic strata over 7000m thick and good hydrocarbon accumulation conditions. Amplitude attribute of -90°phase component derived by phase decomposition is employed to detect Hydrocarbon in the zone of interest (ZOI) in Chaoshan Depression. And it is found that there are evident amplitude anomalies occurring around ZOI. Phase decomposition is applied to forward modeling results of the ZOI, and high amplitudes occur on the -90°phase component more or less when ZOI is charged with hydrocarbon, which shows that the amplitude abnormality in ZOI is probably caused by oil and gas accumulation

Difference in the regulation of IL-8 expression induced by uropathogenic E. coli between two kinds of urinary tract epithelial cells

Bacterial adherence to epithelial cells is a key virulence trait of pathogenic bacteria. The type 1 fimbriae and the P-fimbriae of uropathogenic Escherichia coli (UPEC) have both been described to be important for the establishment of urinary tract infections (UTI). To explore the interactions between the host and bacterium responsible for the different environments of UPEC invasion, we examined the effect of pH and osmolarity on UPEC strain J96 fimbrial expression, and subsequent J96-induced interleukin-8 (IL-8) expression in different uroepithelial cells. The J96 strain grown in high pH with low osmolarity condition was favorable for the expression of type 1 fimbriae; whereas J96 grown in low pH with high osmolarity condition was beneficial for P fimbriae expression. Type 1 fimbriated J96 specifically invaded bladder 5637 epithelial cells and induced IL-8 expression. On the contrary, P fimbriated J96 invaded renal 786-O epithelial cells and induced IL-8 expression effectively. Type 1 fimbriated J96-induced IL-8 induction involved the p38, as well as ERK, JNK pathways, which leads to AP-1-mediated gene expression. P fimbriated J96-induced augmentation of IL-8 expression mainly involved p38-mediated AP-1 and NF-κB transcriptional activation. These results indicate that different expression of fimbriae in J96 trigger differential IL-8 gene regulation pathways in different uroepithelial cells