IFCC reference measurement procedure for substance concentration determination of total carbon dioxide in blood, plasma or serum

A reference measurement procedure for substance concentration determination of total CO, in blood, plasma (the anticoagulant is usually heparin) or serum is described. The document covers the principle of the method, the materials and equipment needed and essential aspects of the procedure. The substance concentration of total CO, in blood, plasma or serum is accurately determined and therefore this procedure is recommended for assigning reference values to reference materials and for blood gas quality assurance in laboratories and by manufacturers of blood gas equipment

IFCC reference measurement procedure for substance concentration determination of total carbon dioxide in blood, plasma or serum

A reference measurement procedure for substance concentration determination of total CO, in blood, plasma (the anticoagulant is usually heparin) or serum is described. The document covers the principle of the method, the materials and equipment needed and essential aspects of the procedure. The substance concentration of total CO, in blood, plasma or serum is accurately determined and therefore this procedure is recommended for assigning reference values to reference materials and for blood gas quality assurance in laboratories and by manufacturers of blood gas equipment.</p

Use of ion-selective electrodes for blood-electrolyte analysis. Recommendations for nomenclature, definitions and conventions

This paper will familiarize the reader with the terms used to describe the behavior of ion-selective electrodes, particularly in relation to their use in clinical chemistry for determination of blood electrolyte cations. It serves as an introduction to a series of papers dealing with important cations in blood, namely calcium, sodium, and potassium. The detailed relationships between the ion activity determined by means of ion-selective electrode potentiometry in undiluted specimens, and the total substance concentration measured by flame atomic-emission spectrometry are described by flow chart and equations. Adoption of a convention for reporting results is recommended. The Working Group on Selective Electrodes has taken into account recent revisions of IUPAC recommendations on nomenclature and selectivity coefficient determinations for ion-selective electrodes, and benefited from the experience of a member of the WG, who was also involved in the IUPAC discussions. Nomenclature for determined quantities follows previous IUPAC/IFCC joint recommendations