2 research outputs found
Nodular AL Amyloidosis — An Unusual Etiology of a Solitary Pulmonary Nodule
Solitary pulmonary nodules (SPN) are defined as single intraparenchymal opacities less than 3 centimeters. The differential diagnosis of the SPN is broad. AL amyloidosis is a protein conformational disease which occurs when certain monoclonal light chains develop an unstable tertiary structure with resultant polymerization of insoluble amyloid fibrils that deposit in the extracellular space of sundry tissues. In the lung, diffuse interstitial amyloid deposition is the most common form of the disease
Pulmonary Metastases of Basal Cell Adenocarcinoma Presenting as Hemoptysis
Basal Cell Adenocarcinoma (BCAC) is a rare malignancy, only accounting for approximately 2% of all salivary neoplasms. Considered the malignant counterpart of basal cell adenoma, it most commonly presents at 60 years of age without gender predilection. Sites of involvement frequently includes the parotid gland, but sites in the minor salivary glands, nasopharynx, buccal mucosa, and tongue have also been reported. Often regarded as an indolent malignancy, BCAC can occasionally cause invasive disease and infrequently, metastatic disease. Among all solid tumors, endobronchial metastases is quite a rare occurrence, contributing to approximately 4% of endobronchial biopsies4. Most common sites of metastases in BCAC include cervical lymph nodes with sparse reports of pulmonary, hepatic and cutaneous involvement5. We present a case of endobronchial metastases from BCAC of the base of the tongue