NF-KB protein purification from bovine spleen: Nucleotide stimulation and binding site specificity

The activity of the enhancer for the κ immunoglobulin light chain gene critically depends on the presence in the nucleus of the NF-κB protein. We purified NF-κB over 50,000-fold and identified two protein species, 42 and 44 kDa, that could be eluted and renatured from a sodium dodecyl sulfate/polyacrylamide gel to give specific DNA-binding activity. Binding of the purified bovine NF-κB as well as that from human and murine B- or T-lymphoid cell extracts was dramatically stimulated by nucleoside triphosphates. This effect distinguished NF-κB from a related factor, H2-TF1. Purified NF-κB interacted efficiently with regulatory sequences that function during either B- or T-lymphocyte activation, including the human immunodeficiency virus enhancer and a NF-κB binding site we detected in the interleukin 2 enhancer

Probing Electroweak Symmetry Breaking Mechanism at the LHC: A Guideline from Power Counting Analysis

We formulate the equivalence theorem as a theoretical criterion for sensitively probing the electroweak symmetry breaking mechanism, and develop a precise power counting method for the chiral Lagrangian formulated electroweak theories. Armed with these, we perform a systematic analysis on the sensitivities of the scattering processes $W^\pm W^\pm \rightarrow W^\pm W^\pm$ and $q\bar{q}'\rightarrow W^\pm Z$ for testing all possible effective bosonic operators in the chiral Lagrangian formulated electroweak theories at the CERN Large Hadron Collider (LHC). The analysis shows that these two kinds of processes are "complementary" in probing the electroweak symmetry breaking sector.Comment: Extended version, 11-page-Latex-file and 3 separate PS-Figs. To be Published in Mod.Phys.Lett.

Identification of the age-period-cohort model and the extended chain ladder model

In this paper, we consider the identification problem arising in the age-period-cohort models, as well as in the extended chain ladder model. We propose a canonical parametrization based on the accelerations of the trends in the three factors. This parametrization is exactly identified. It eases interpretation, estimation and forecasting. The canonical parametrization is shown to apply for a class of index sets which have trapezoid shapes, including various Lexis diagrams and the insurance reserving triangles.

QCD Multipole Expansion and Hadronic Transitions in Heavy Quarkonium Systems

We review the developments of QCD multipole expansion and its applications to hadronic transitions and some radiative decays of heavy quarkonia. Theoretical predictions are compsred with updated experimental results.Comment: 23 pages, 7 figures. Some typos corrected, and 3 references adde