Human protein reference database—2006 update

Human Protein Reference Database (HPRD) () was developed to serve as a comprehensive collection of protein features, post-translational modifications (PTMs) and protein–protein interactions. Since the original report, this database has increased to >20 000 proteins entries and has become the largest database for literature-derived protein–protein interactions (>30 000) and PTMs (>8000) for human proteins. We have also introduced several new features in HPRD including: (i) protein isoforms, (ii) enhanced search options, (iii) linking of pathway annotations and (iv) integration of a novel browser, GenProt Viewer (), developed by us that allows integration of genomic and proteomic information. With the continued support and active participation by the biomedical community, we expect HPRD to become a unique source of curated information for the human proteome and spur biomedical discoveries based on integration of genomic, transcriptomic and proteomic data

Concept design of an installation vessel to install fully assembled next generation offshore wind energy turbines

The shifting of the European energy market towards the wind energy means there will be more wind farms developed in deeper water and farther away from the shore. The existing infrastructure being used for installation is seldom purpose-built for this task, resulting in delays and consequently loss of money for the operators and contractors. Furthermore, the existing process is labor intensive, time consuming and not very safe, the vessels are limited by design to work in moderate sea conditions that for instance exist in the North Sea during the summer season. Seaway Heavy Lifting has been actively involved in solutions for the single lift installation of wind turbine generators (WTG’s). This thesis is to investigate whether there can be a new concept based on improved hull shapes to install WTG’s in a single lift operation more efficiently. The study involves the development of a concept which can provide safe and speedy transportation and installation of fully assembled next generation WTG’s. The selection of the hull shape is based on an extensive but subjective multi criteria analysis using the mission profile and functional requirements of the vessel and available research & operational data. Most important criteria used are: sufficient capacity to carry 8 completely assembled WTG’s of 7MW in vertical position on deck, sufficient speed potential for good North Sea logistics, good motion characteristics for high installation work-ability, sufficient stability to perform the lifting task. From the multi criteria analysis the SWATH (small water plane area twin hull) appears to be the most promising hull shape and is therefore selected for further analysis. Because Seaway Heavy Lifting has more than two decades experience with mono hull heavy lift vessels, a dual draft mono hull vessel dedicated for WTG installation is also analysed for reference. The dimensions of both vessels are determined based on a parametric study in order to comply with the various design requirements. The required deck area and layout together with the strict stability requirements like drop load criteria and intact stability turned out to be important for overall dimensions of both the SWATH and dual draft mono hull. Furthermore a sensitivity analysis is done on these dimensions to check which ones affect the operability of the SWATH. The stability calculations are validated with the help of recognized stability software. Different speed scenarios are evaluated for a given location to check the dependence on vessel speed, resistance and power requirements which could limit the operability. Based on the derived dimensions both vessels are subjected to multi-body frequency domain motion analysis using a recognized hydrodynamics program. Subsequently the workability of both vessels is investigated using very detailed 2D wave spectral data available for an important North Sea wind farm development area. The results of this thesis are the first steps towards establishing the SWATH as a viable option for operating as a WTG installation vessel. The motion behavior of the SWATH is better than the mono hull in certain important operational conditions. There are some significant advantages which the SWATH exhibits over the Monohull and other hull forms which can be utilized for the purpose of WTG installation and helps in avoiding complex installation systems and techniques to get safe and fast operation.Floating StructuresOffshore & Dredging EngineeringMechanical, Maritime and Materials Engineerin

Effect of nickel doping on magnetic and dielectric properties of orthorhombic calcium ferrite nanoparticles

Nickel (10∼50 mol%) doped calcium ferrite nanoparticles (NPs) are synthesized by the solution combustion method using lemon juice extract as a reducing agent, followed by calcination at 500°C. The calcined samples are characterized with different techniques. The Bragg reflections of Nickel doping confirm the formation of a single orthorhombic calcium ferrite phase. The crystallite size is estimated using both Scherrer's and the W-H plot method. The surface morphology consists of irregular size and shaped agglomerated NPs along with pores and voids. A blueshift and a broad absorption spectrum is observed with an increase in the direct energy band gap. The direct energy band gap estimated from Wood and Tauc's relationship was found to be 2.91∼2.97 eV with an increase in dopant concentration. The magnetic analysis provided values for saturation magnetization (Ms), remanence (Mr), and coercivity (Hc), while dielectric studies demonstrated a dielectric constant of 2.81, 2.14, and 1.67 with increasing dopant concentration. The variation of dielectric properties of the sample as a function of frequency in the range 0.1∼20 MHz has been studied at room temperature. The dielectric properties of CaFe2O4: Ni (1∼9 mol%) NPs clearly indicate that there is a more pronounced dispersion at lower frequencies, gradually reaching saturation as the frequency increases. The dielectric loss was found to decrease from 4.62, 3.22, and 2.32 with an increase in Ni2+ substitution (10, 30, and 50 mol%) respectively. These results indicate the suitability of these samples for applications in memory devices and high-frequency applications

Dataset on the importation of the exotic shrimp Penaeus vannamei broodstock (Boone, 1931) to India

Penaeus vannamei is an exotic shrimp species that has gained high culture momentum, since its introduction to India [1]. Currently, the culture of the species in the Country is being done by the shrimp farmers by importation of Specific Pathogen Free (SPF) vannamei broodstock from approved suppliers, which are located overseas. The value of one brooder normally ranges from 50 to 61 US $, excluding the custom duty, processing fee and other charges for the transboundary shipment of the stock to India. The P. vannamei stock are permitted to be imported to the Country by the hatchery operators only through the single declared port of entry, i.e. Chennai in Tamil Nadu in the Country. The imported parent shrimps are then to be quarantined at the Aquatic Quarantine Facility before being transported to the vannamei hatcheries [2]. This article reports the data available on import of vannamei broodstock to India since its importation to India in 2009. The dataset presented here contains information on transit and quarantine mortality of the brooders following the shipment of the stock by the various broodstock suppliers from the overseas