18 research outputs found
STM conductance of Kondo impurities on open and structured surfaces
We study the scanning tunneling microscopy response for magnetic atoms on
open and structured surfaces using Wilson's renormalization group. We observe
Fano resonances associated with Kondo resonances and interference effects. For
a magnetic atom in a quantum corral coupled to the confined surface states, and
experimentally relevant parameters, we observe a large confinement induced
effect not present in the experiments. These results suggest that the Kondo
screening is dominated by the bulk electrons rather than the surface ones.Comment: 6 pages, 6 figure
Effector cell mediated cytotoxicity measured by intracellular Granzyme B release in HIV infected subjects
CD8+ cytotoxic T lymphocyte (CTL) activity is currently believed to be one of the key immunologic mechanisms responsible for the prevention or attenuation of HIV-1 infection. The induction of CD8+ T cell activation may also result in the production of soluble or non-classical lytic factors that are associated with protection from infection or slower disease progression. Traditionally, CD8+ CTL responses have been measured by the classic chromium release assay, monitoring the ability of T cells (Effector cells) to lyse radiolabelled HLA – matched “target cells” that express the appropriate antigen-MHC complex. This method is not only labor intensive, semi quantitative assay at best, but also needs fresh, non-cryopreserved cells. Recently, cytokine specific ELISPOT assays or tetrameric MHC-I/ peptide complexes have utilized to directly quantitate circulating CD8+ effector cells, and these assays are more sensitive, quantitative and reproducible than the traditional CTL lysis assay and can also be performed on cryopreserved cells. Although these are reproducible assays for the assessment of soluble antiviral activity secreted by activated T cell populations they can be extremely expensive to perform. We have used FACS Analysis to measure Granzyme B release as a function of cell mediated cytotoxicity. This method helps quantitate the CTL activity and also identifies the phenotype of the cells elucidating this immune response. The method described not only monitors immunological response but also is also simple to perform, precise and extremely time efficient and is ideal for screening a large number of samples
Hybrid management of a spontaneous ilio-iliac arteriovenous fistula: a case report
<p>Abstract</p> <p>Introduction</p> <p>Spontaneous iliac arteriovenous fistulae are a rare clinical entity. Such localized fistulation is usually a result of penetrating traumatic or iatrogenic injury. Clinical presentation can vary greatly but commonly includes back pain, high-output congestive cardiac failure and the presence of an abdominal bruit. Diagnosis, therefore, is often incidental or delayed.</p> <p>Case presentation</p> <p>We report a case of a spontaneous ilio-iliac arteriovenous fistula in a 68-year-old Caucasian man detected following presentation with unilateral claudication and congestive cardiac failure. Following computed tomography evaluation, the fistula was successfully treated with a combined endovascular (aorto-uni-iliac device) and open (femoro-femoral crossover) approach.</p> <p>Conclusion</p> <p>Endovascular surgery has revolutionized the management of such fistulae and we report an interesting case of a high-output iliac arteriovenous fistulae successfully treated with a hybrid vascular approach.</p
Spectral function of the Kondo model in high magnetic fields
Using a recently developed perturbative renormalization group (RG) scheme, we
calculate analytically the spectral function of a Kondo impurity for either
large frequencies w or large magnetic field B and arbitrary frequencies. For
large w >> max[B,T_K] the spectral function decays as 1/ln^2[ w/T_K ] with
prefactors which depend on the magnetization. The spin-resolved spectral
function displays a pronounced peak at w=B with a characteristic asymmetry. In
a detailed comparison with results from numerical renormalization group (NRG)
and bare perturbation theory in next-to-leading logarithmic order, we show that
our perturbative RG scheme is controlled by the small parameter 1/ln[
max(w,B)/T_K]. Furthermore, we assess the ability of the NRG to resolve
structures at finite frequencies.Comment: 8 pages, version published in PRB, minor change
Computer Graphics in Education A Distributed Rendering Environment for Teaching Animation and
Scientifi
Automated Grid-Probe System to Improve End-To-End Grid Reliability for a Science Gateway
In 2010, the science gateway nanoHUB.org, the world’s largest nanotechnology user facility, hosted 9,809 simulation users who performed 372,404 simulation runs. Many of these jobs are compute-intensive runs that benefit from submission to clusters at Purdue, TeraGrid, and Open Science Grid (OSG). Most of the nanoHUB users are not computational experts but end-users who expect complete and uninterrupted service. Within the ecology of grid computing resources, we need to manage the grid submissions of these users transparently with the highest possible degree of user satisfaction. In order to best utilize grid computing resources, we have developed a grid probe protocol to test the job submission system from end to end. Beginning in January 2009, we have collected a total of 1.2 million probe results from job submissions to TeraGrid, OSG, Purdue, and nanoHUB compute clusters. We then utilized these results to intelligently submit jobs to various grid sites using a model for probability of success based in part on probe test history. In this paper we present details of our grid probe model, results from the grid probe runs, and a discussion of data from production runs over the same time period. These results have allowed us to begin assessing our utilization of grid resources while providing our users with satisfactory outcomes
Wintertime aerosol characteristics over the Indo‐Gangetic Plain (IGP): Impacts of local boundary layer processes and long‐range transport
Wintertime aerosol character istics over the Indo-Gangetic Plain (IGP): impacts of local boundary layer processes and long-range transport
The Indo-Gangetic Plain (IGP) encompasses a vast area, (accounting for ∼21% of the land area of India), which is densely populated (accommodating ∼40% of the Indian population). Highly growing economy and population over this region results in a wide range of anthropogenic activities. A large number of thermal power plants (most of them coal fed) are clustered along this region. Despite its importance, detailed investigation of aerosols over this region is sparse. During an intense field campaign of winter 2004, extensive aerosol and atmospheric boundary layer measurements were made from three locations: Kharagpur (KGP), Allahabad (ALB), and Kanpur (KNP), within the IGP. These data are used (1) to understand the regional features of aerosols and BC over the IGP and their interdependencies, (2) to compare it with features at locations lying at far away from the IGP where the conditions are totally different, (3) to delineate the effects of mesoscale processes associated with changes in the local atmospheric boundary layer (ABL), (4) to investigate the effects of long-range transport or moving weather phenomena in modulating the aerosol properties as well as the ABL characteristics, and (5) to examine the changes as the season changes over to spring and summer. Our investigations have revealed very high concentrations of aerosols along the IGP, the average mass concentrations (M T) of total aerosols being in the range 260 to 300 μg m−3 and BC mass concentrations (M B) in the range 20 to 30 μg m−3 (both ∼5 to 8 times higher than the values observed at off-IGP stations) during December 2004. Despite, BC constituted about 10% to the total aerosol mass concentration, a value quite comparable to those observed elsewhere over India for this season. The dynamics of the local atmospheric boundary layer (ABL) as well as changes in local emissions strongly influence the diurnal variations of M T and M B, both being inversely correlated with the mixed layer height (Z i) and the ventilation coefficient (V c). The share of BC to total aerosols is highest (∼12%) during early night and lowest (∼4%) in the early morning hours. While an increase in the V c results in a reduction in the concentration almost simultaneously, an increase in Z imax has its most impact on the concentration after ∼1 day. Accumulation mode aerosols contributed ∼90% to the aerosol concentration at ALB, ∼77 % at KGP and 74% at KNP. The BC mass mixing ratio was ∼10% over all three locations and is comparable to the value reported for Trivandrum, a tropical coastal location in southern India. This indicates presence of submicron aerosols species other than BC (such as sulfate) over KGP and KNP. A cross-correlation analysis showed that the changes in M B at KGP is significantly correlated with those at KNP, located ∼850 km upwind, and ALB after a delay of ∼7 days, while no such delay was seen between ALB and KNP. Back trajectory analyses show an enhancement in M B associated with trajectories arriving from west, the farther from to the west they arrive, the more is the increase. This, along with the ABL characteristics, indicate two possibilities: (1) advection of aerosols from the west Asia and northwest India and (2) movement of a weather phenomena (such as cold air mass) conducive for build up of aerosols from the west to east. As the winter gives way to summer, the change in the wind direction and increased convective mixing lead to a rapid decrease in M B