MGMT 469 Business Policy

Course syllabus for MGMT 469 Business Policy Course description: This is the capstone course of the B.A. in Business Administration. The course is designed to integrate the various functional areas of business and administration through case discussion that applies management, finance, production, marketing, economics, and accounting principles to solving business problems. This course is about strategic management systems in action. The course will discuss the concept of a strategic framework for the organization, and the aligning of component and subsidiary parts of the organization into that framework, including both long-term and short-term enactment, accountability, and performance reporting. Discussions regarding the linkages between management processes and strategies will also be included. The challenge for each student will be to develop an understanding of what new management practices and behaviors will be needed to support a strategic management system

Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine

Liposomal encapsulated cytarabine (DepoCyte®, Mundipharma GmbH, Limburg/Lahn, Germany) is a slow-release formulation of conventional cytarabine. It is licensed for intrathecal use in patients with lymphomatous and leukemic meningitis. DepoCyte® obtained superior response rates, improved patient quality of life and improved the time to neurological progression in a randomized albeit small clinical trial. In this review we briefly summarize the clinical data and discuss them in light of clinical problems and possible treatment scenarios

Verpackungsmaterial und Schmierstoffe aus nachwachsenden Rohstoffen : Tagungsband zur Veranstaltung des Zentrums für Europäische Wirtschaftsforschung und der Industrie- und Handelskammer-Karlsruhe am 23. Februar 1994 im Rahmen der IHK-Veranstaltungsreihe "Betrieblicher Umweltschutz"

Mit der 5. Novelle des Abfallgesetzes hat die Bundesregierung im Frühjahr 1993 den Entwurf eines Kreislaufwirtschafts- und Abfallgesetzes verabschiedet. Die Wirtschaft soll dadurch verstärkt die Verantwortung für die hergestellten Produkte über den gesamten Lebensweg wahrnehmen. Vor diesem Hintergrund veranstalteten das Zentrum für Europäische Wirtschaftsforschung und das Referat Energiewirtschaft und Umweltschutz der Industrie und Handelskammer Karlsruhe am 23. Februar 1994 im Rahmen der IHK-Veranstaltungsreihe "Betrieblicher Umweltschutz" ein Seminar zum Thema "Verpackungsmaterial und Schmierstoffe aus nachwachsenden Rohstoffen". Vertreter aus Forschung und Praxis referierten dabei über die Einsatzmöglichkeiten, die Umweltauswirkungen und die Wirtschaftlichkeit nachwachsender Rohstoffe im Verpackungs- und Schmierstoffmittelbereich

Verpackungsmaterial und Schmierstoffe aus nachwachsenden Rohstoffen: Tagungsband zur Veranstaltung des Zentrums für Europäische Wirtschaftsforschung und der Industrie- und Handelskammer-Karlsruhe am 23. Februar 1994 im Rahmen der IHK-Veranstaltungsreihe

--

Integrating patient reported measures as predictive parameters into decisionmaking about palliative chemotherapy: a pilot study

Background: Systemic treatment has proven to improve physical symptoms in patients with advanced cancer. Relationship between quality of life (QoL) or symptom burden (SYB) and treatment efficacy (tumour response and survival) is poorly described. Therefore, we evaluated the predictive value of pretreatment QoL and SYB on treatment outcomes. Methods: Eligible patients had metastatic gastrointestinal cancers and were about to receive 1st/2nd line palliative chemotherapy. 47 patients were consecutively enrolled. QoL and SYB were assessed by EORTC QLQ-C30 and MSKCC MSAS questionnaires before treatment and after first response evaluation after 8–12 weeks. Logistic regression analysis of QoL and SYB for prediction of objective treatment efficacy was performed. Patients were categorized according to response rate (RR) based on RECIST1.1 and progression free survival (PFS). PFS was categorized by a ratio (individual PFS/expected PFS) in above median (ratio > 1) or below median PFS (ratio 10 points difference). Lowest scores in all functioning scales at treatment start were seen in patients with future PFSR < 1. Global health status (EORTC), PSYCH subscale and global distress index (MSAS) predicted PFSR, even if adjusted for gender, age, cancer type, ECOG and line of treatment (p < 0.05). Interestingly, improved QoL and SYB (subjective benefit) were noted even in patients with worse pretreatment status and no objective tumour response. Conclusion: Future non-responders seem to show distinct QoL patterns before chemotherapy. This may facilitate early detection of patients deriving less or even no benefit from treatment regarding prolongation of survival. Even in patients with primarily progressive disease QoL and SYB may improve during treatment. Integration of QoL and SYB assessment into decision-making about palliative chemotherapy seem to be an important approach to improve patient outcome and should be further evaluated

Does Physical Activity Improve Quality of Life in Cancer Patients Undergoing Chemotherapy?

Background: Improved cancer treatments have resulted in prolonged survival. Nevertheless, tumor symptoms and side effects still compromise physical activity and quality of life (QoL). Patients and Methods: We conducted an anonymous survey among cancer patients undergoing chemotherapy using standardized questionnaires: the ‘Freiburger Fragebogen zur körperlichen Aktivität’ (Freiburg Questionnaire on Physical Activity) and European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30. Two main questions were addressed: were there differences (1) in physical activity and QoL between patients who do not believe that sport could improve their QoL and those who believe it could (group A vs. B); and (2) in QoL between patients with a total activity (TA) < 18 metabolic equivalent of task (MET) h/week and those with a TA of ˰ 18 MET h/week (group C vs. D)? Results: 276 of 400 questionnaires were completed. Groups A and B were balanced in terms of baseline characteristics. Group A suffered significantly more from fatigue and pain; group B reported higher levels of global health status (GHS) and TA. Groups C and D differed in gender distribution, age, and educational background. Group D had significantly higher levels of GHS, group C suffered more from fatigue, pain, and appetite loss. Conclusion: Physical activity correlates with a better QoL of cancer patients undergoing chemotherapy