Underground Test Area Fiscal Year 2013 Annual Quality Assurance Report Nevada National Security Site, Nevada, Revision 0

This report is required by the Underground Test Area (UGTA) Quality Assurance Plan (QAP) and identifies the UGTA quality assurance (QA) activities for fiscal year (FY) 2013. All UGTA organizations—U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO); Desert Research Institute (DRI); Lawrence Livermore National Laboratory (LLNL); Los Alamos National Laboratory (LANL); Navarro-Intera, LLC (N-I); National Security Technologies, LLC (NSTec); and the U.S. Geological Survey (USGS)—conducted QA activities in FY 2013. The activities included conducting assessments, identifying findings and completing corrective actions, evaluating laboratory performance, and publishing documents. In addition, integrated UGTA required reading and corrective action tracking was instituted

Assurance Requirements Compliance for the Greater Confinement Disposal Boreholes, Area 5 Radioactive Waste Management Site, Nevada Test Site

This paper addresses deficiencies identified with the. Performance Assessment for Greater Confinement Disposal (GCD) Boreholes compliance with the Title 40 Code of federal Regulations (CFR) Part 191.14, "Assurance Requirements" (CFR, 1985). The Transuransic Waste Disposal Federal Review Group (TFRG). and U.S Department of Energy Headquarters , need to concur that the assurance requirements have been met at the time of closure of the Area 5 Radioactive Waste Management Site

Right-sided resection with standard or selective portal vein resection in patients with perihilar cholangiocarcinoma: a propensity score analysis

Background: Standard portal vein resection (PVR) has been proposed to improve oncological outcomes in patients with perihilar cholangiocarcinoma (PHC), however it potentially introduces an increased risk of morbidity. The policy in Amsterdam UMC(AMC) is to resect the portal vein bifurcation selectively when involved, while in Charité-Universitätsmedizin Berlin, standard PVR is performed with right trisectionectomy. The objective of this study was to analyze postoperative outcomes and survival after standard or selective PVR for PHC. Methods: A retrospective study was performed including PHC-patients undergoing right-sided resection in Amsterdam (2000–2018) and Berlin (2005–2015). Primary outcomes were 90-day mortality, severe morbidity (Clavien-Dindo≥3), and overall survival (OS). A propensity score comparison (1:1 ratio) was performed corrected for age/sex/ASA/jaundice/tumor diameter/N-stage/Bismuth-Corlette type-IV. Results: A total of 251 patients who underwent right-sided resection for PHC were evaluated: 87 in the selective (Amsterdam) and 164 in the standard PVR-group (Berlin). Major differences in baseline characteristics were observed, with higher ASA and AJCC-stage in the standard PVR-group (Berlin). Severe morbidity and 90-day mortality were comparable before matching (selective/Amsterdam:68% and 19%, standard/Berlin:61% and 17%,p = 0.284 and p = 0.746, respectively). After propensity score matching, both short term outcomes and OS were comparable (selective/Amsterdam (n = 45) 33 months (95%CI:20–45), standard/Berlin (n = 45) 31 months (95%CI:24–38,p = 0.747)). Conclusion: In this combined cohort, standard PVR was not associated with increased severe morbidity or mortality. After propensity score matching, survival was comparable after selective (Amsterdam) and standard PVR (Berlin)