Рroblem of Student’s Physical Health as Well as to Sanitary Measures that Take Place in the Educational Process of Students.

Висвітлено проблему фізичного здоров’я студентів та оздоровчі заходи в супроводі навчання студентів. Проблема фізичного здоров’я полягає у порушенні адаптивного потенціалу системи кровообігу, що пов’язано з неправильним способом життя. This article is devoted to the problem of student’s physical health as well as to sanitary measures that take place in the educational process of students. The problems of physical health lie in the breach of blood circulation adaptable that is connected with unhealthy way of life

Functional Identification of Catalytic Metal Ion Binding Sites within RNA

The viability of living systems depends inextricably on enzymes that catalyze phosphoryl transfer reactions. For many enzymes in this class, including several ribozymes, divalent metal ions serve as obligate cofactors. Understanding how metal ions mediate catalysis requires elucidation of metal ion interactions with both the enzyme and the substrate(s). In the Tetrahymena group I intron, previous work using atomic mutagenesis and quantitative analysis of metal ion rescue behavior identified three metal ions (MA, MB, and MC) that make five interactions with the ribozyme substrates in the reaction's transition state. Here, we combine substrate atomic mutagenesis with site-specific phosphorothioate substitutions in the ribozyme backbone to develop a powerful, general strategy for defining the ligands of catalytic metal ions within RNA. In applying this strategy to the Tetrahymena group I intron, we have identified the pro-SP phosphoryl oxygen at nucleotide C262 as a ribozyme ligand for MC. Our findings establish a direct connection between the ribozyme core and the functionally defined model of the chemical transition state, thereby extending the known set of transition-state interactions and providing information critical for the application of the recent group I intron crystallographic structures to the understanding of catalysis.</p

Functional Identification of Catalytic Metal Ion Binding Sites within RNA

The viability of living systems depends inextricably on enzymes that catalyze phosphoryl transfer reactions. For many enzymes in this class, including several ribozymes, divalent metal ions serve as obligate cofactors. Understanding how metal ions mediate catalysis requires elucidation of metal ion interactions with both the enzyme and the substrate(s). In the Tetrahymena group I intron, previous work using atomic mutagenesis and quantitative analysis of metal ion rescue behavior identified three metal ions (M(A), M(B), and M(C)) that make five interactions with the ribozyme substrates in the reaction's transition state. Here, we combine substrate atomic mutagenesis with site-specific phosphorothioate substitutions in the ribozyme backbone to develop a powerful, general strategy for defining the ligands of catalytic metal ions within RNA. In applying this strategy to the Tetrahymena group I intron, we have identified the pro-S (P) phosphoryl oxygen at nucleotide C262 as a ribozyme ligand for M(C). Our findings establish a direct connection between the ribozyme core and the functionally defined model of the chemical transition state, thereby extending the known set of transition-state interactions and providing information critical for the application of the recent group I intron crystallographic structures to the understanding of catalysis

GARFIELD + RCo Digital Upgrade: a Modern Set-up for Mass and Charge Identification of Heavy Ion Reaction Products

An upgraded GARFIELD + Ring Counter (RCo) apparatus is presented with improved performances as far as electronics and detectors are concerned. On one side fast sampling digital read out has been extended to all detectors, allowing for an important simplification of the signal processing chain together with an enriched extracted information. On the other side a relevant improvement has been made in the forward part of the setup (RCo): an increased granularity of the CsI(Tl) crystals and a higher homogeneity in the silicon detector resistivity. The renewed performances of the GARFIELD + RCo array make it suitable for nuclear reaction measurements both with stable and with Radioactive Ion Beams (RIB), like the ones foreseen for the SPES facility, where the Physics of Isospin can be studied.Comment: 13 pages, 19 figures - paper submitted to Eur. Phys. J.

Isotope analysis in central heavy ion collisions at intermediate energies

Symmetry energy is a key quantity in the study of the equation of state of asymmetric nuclear matter. Heavy ion collisions at low and intermediate energies, performed at Laboratori Nazionali di Legnaro and Laboratori Nazionali del Sud, can be used to extract information on the symmetry energy coefficient Csym, which is currently poorly known but relevant both for astrophysics and for structure of exotic nuclei.Comment: 2 pages, 1 figure. Proceedings of 7th International Conference on Radioactive Nuclear Beams (RNB7), to be published in The European Physical Journal

Системы и технологии пневматического золоудаления ТЭС

В Європейському союзі, США та інших розвинутих країнах світу зола електростанцій розглядається як техногенна сировина для багатьох галузей промисловості, яка утилізується до 92% в сухому вигляді, їх системи пневмозоловидалення є невід’ємною складовою технологічного процесу вугільних ТЕС. В Україні застосовуються системи гідрозоловидалення, і як наслідок, зола втрачає свої споживчі цінності щодо такого використання, а її накопичення на золовідвалах приводить до проблем землевідведення, забруднення грунту, водойм, атмосфери, запилення територій, можливості катастрофічних наслідків від прориву огородження дамб, рішенням яких є утилізація золи в сухому вигляді. В статті наведено порівняльний аналіз відомих систем пневмозоловидалення (за фазою щільності, характером транспортування, способу створення в трубопроводі різниці тиску), надано рекомендації щодо вибору обладнання та технологій, які отримали позитивну апробацію в світі. Їх використання на вугільних ТЕС України дозволить максимально утилізувати золу як цінний продукт, отримати прибуток від збуту, вирішувати проблеми охорони навколишнього середовища.In the European Union, the USA and other developed countries of the world the ashes of power plants are considered as technogenic raw materials for many industries, which are utilized to 92 % in a dry form; their systems of pneumatic ash handling are an integral part of technological process of coal-fired TPPs. In Ukraine the systems of hydraulic ash removal are applied and, as a consequence, ashes lose the consumer worth concerning such use, and its accumulation in ash dumps leads to land allotment problems, pollution of soil, ponds, atmosphere, pollination of territories, and possibility of catastrophic aftereffects from breakthrough of protections dams, which solution is the disposal of ash in dry form. The article presents a comparative analysis of the known systems of pneumatic ash handling (on the density phase, nature of the transportation, method of creating a pressure difference in a pipeline),the recommendations are given on the choice of equipment and technologies, which have obtained the positive approbation in the world. Their use in the coal-fired TPPs of Ukraine will allow to the maximum dispose of the ash as a valuable product, to obtain a profit from sales, and to solve problems of environmental protection.В Европейском союзе, США и других развитых странах мира зола электростанций рассматривается как техногенное сырье для многих отраслей промышленности, которая утилизируется до 92% в сухом виде, их системы пневмозолоудаления есть неотъемлемой составной технологического процесса угольных ТЭС. В Украине применяются системы гидрозолоудаления и, как следствие, зола теряет свои потребительские ценности относительно такого использования, а ее накопление на золоотвалах приводит к проблемам землеотвода, загрязнения грунту, водоемов, атмосферы, опыления территорий, возможности катастрофических следствий от прорыва ограждения дамб, решением которых является утилизация золы в сухом виде. В статье приведенный сравнительный анализ известных систем пневмозолоудаления (за фазой плотности, характером транспортировки, способа создания в трубопроводе разности давления), предоставлены рекомендации относительно выбора оборудования и технологий, которые получили положительную апробацию в мире. Их использование на угольных ТЭС Украины позволит максимально утилизировать золу как ценный продукт, получить прибыль от сбыта, решать проблемы охраны окружающей среды

ПЕРЕДУМОВИ, ЗАВДАННЯ І ФОРМИ РАДЯНІЗАЦІЇ ОСВІТИ НА ТЕРНОПІЛЬЩИНІ У ВЕРЕСНІ 1939 – ЧЕРВНІ 1941 РОКУ

The proposed article reflects the mechanisms of implementation of the new Soviet educational and cultural values that reflect the Marxist-Leninist ideology, which was based on an international worldview class contradictions and constant struggle against private property, destroying religious beliefs of the local population.  The so-called reform contradicts the nature of Ukrainian national ideology, destroying its cultural and educational heritage of centuries. For this purpose, the new Soviet government introduces in all Western -Ukrainian schools as second Russian language as a means of international communication and academic educational network of country subordinates to one Moscow’s educational-methodical center.У пропонованій статті висвітлено механізми впровадження радянських освітньо-культурних цінностей, які відображали марксистсько-ленінську ідеологію, що ґрунтувалася на інтернаціональному світобаченні класових протиріч та постійній боротьбі з приватною власністю, руйнуючи релігійні переконання місцевого населення. Так звана реформа протирічила природі українського національного світогляду, нищила його культурно-освітні  багатовікові надбання. З цією метою радянська влада запроваджувала в усіх західноукраїнських школах другу російську мову, як засіб міжнаціонального спілкування, а також освітню виховну мережу краю підпорядковувала єдиному Московському освітньо-методичному центру

Forensic Examination as a Mediation Tool: Genesis and Prospects for Development in the Context of Martial Law and Post-War Revival of Ukraine

The study explores justice, forensic examination and mediation from the time of their genesis to the present day. The article analyzes historical examples of the application of forensic examination within the mediation process from the Ancient East and Antiquity to the 20th century, as well as the processes of establishing the legitimization of forensic examination (from the end of the 19th century) and mediation (from the end of the 20th century) in Ukraine and abroad. Attention is paid to the prototypes of forensic examination in the times of Kievan Rus, the Principality of Galicia-Volhynia, the Grand Duchy of Lithuania, the Cossack State and the entry of Ukrainian lands into the Austro-Hungarian and Russian empires, as well as the emergence of forensic examination before the First World War and during the Ukrainian Revolution and the expansion of the Bolsheviks and the establishment of Soviet power. The formation of regional offices (1923) and later institutes of scientific and forensic expertise (1925) in Kyiv, Odesa and Kharkiv is studied. The article reveals the peculiarities of the development of forensic examination within the establishment and legitimization of the mediation procedure in independent Ukraine. The provisions of the current legislation on forensic examination and mediation are analyzed. The authors substantiate the prospects of using the results of forensic expert activity for the application of mediation procedures in the settlement of disputes through negotiations between the parties using the conclusions of forensic experts. The authors identify the most promising types of forensic expertise for the mediation procedure (economic, commodity, construction, intellectual property, etc.). The authors determine the prospects for mediators to use expert opinions not only in family, labor, civil, commercial and administrative disputes, but also in criminal cases during martial law and post-war revival of Ukraine