Aquilegia, Vol. 30 No. 5, November-December 2006, Newsletter of the Colorado Native Plant Society

https://epublications.regis.edu/aquilegia/1118/thumbnail.jp

Aquilegia, Vol. 19 No. 1, January-March 1995: Newsletter of the Colorado Native Plant Society

https://epublications.regis.edu/aquilegia/1074/thumbnail.jp

The Grizzly, March 30, 2006

Dr. Edwards Presents Baden Lecture • Student Activism at Ursinus College: Can You Hear Us Now? WeCAN! • Drag Show at Ursinus Anything but a Drag • Circumcision Decision • Stereotypes and Self-Interest: Part Two • Living Off Campus More Trouble Than its Worth? • Brief Conversation with Of Montreal\u27s Kevin Barnes • Opinions: Reimert, a Place to Call Home; The Revolution Will be Printed; Tuition to Increase by $8,492 Next Year • Bears Sweep Eastern in Double Headerhttps://digitalcommons.ursinus.edu/grizzlynews/1710/thumbnail.jp

Erythrocyte adenosine deaminase: diagnostic value for Diamond-Blackfan anaemia

Diamond-Blackfan anaemia (DBA) is an inherited bone marrow failure syndrome (IBMFS) characterized by red cell aplasia. Mutations in ribosomal genes are found in more than 50% of cases. Elevated erythrocyte adenosine deaminase (eADA) was first noted in DBA in 1983. In this study we determined the value of eADA for the diagnosis of DBA compared with other IBMFS; the association of eADA in DBA with age, gender or other haematological parameters; and the association with known DBA-related gene mutations. For the diagnosis of DBA compared with non-DBA patients with other bone marrow failure syndromes, eADA had a sensitivity of 84%, specificity 95%, and positive and negative predictive values of 91%. In patients with DBA there was no association between eADA and gender, age, or other haematological parameters. Erythrocyte ADA segregated with, as well as independent of, known DBA gene mutations. While eADA was an excellent confirmatory test for DBA, 16% of patients with classical clinical DBA had a normal eADA