The End Of Nucleosynthesis: Production Of Lead And Thorium In The Early Galaxy

We examine the Pb and Th abundances in 27 metal-poor stars (-3.1 56) enrichment was produced only by the rapid (r-) nucleosynthesis process. New abundances are derived from Hubble Space Telescope/Space Telescope Imaging Spectrograph, Keck/High Resolution Echelle Spectrograph, and Very Large Telescope/UV-Visual Echelle Spectrograph spectra and combined with other measurements from the literature to form a more complete picture of nucleosynthesis of the heaviest elements produced in the r-process. In all cases, the abundance ratios among the rare earth elements and the third r-process peak elements considered (La, Eu, Er, Hf, and Ir) are constant and equivalent to the scaled solar system r-process abundance distribution. We compare the stellar observations with r-process calculations within the classical "waiting-point" approximation. In these computations a superposition of 15 weighted neutron-density components in the range 23 <= log n(n) <= 30 is fit to the r-process abundance peaks to successfully reproduce both the stable solar system isotopic distribution and the stable heavy element abundance pattern between Ba and U in low-metallicity stars. Under these astrophysical conditions, which are typical of the "main" r-process, we find very good agreement between the stellar Pb r-process abundances and those predicted by our model. For stars with anomalously high Th/Eu ratios (the so-called actinide boost), our observations demonstrate that any nucleosynthetic deviations from the main r-process affect-at most-only the elements beyond the third r-process peak, namely Pb, Th, and U. Our theoretical calculations also indicate that possible r-process abundance "losses" by nuclear fission are negligible for isotopes along the r-process path between Pb and the long-lived radioactive isotopes of Th and U.Deutsche Forschungsgemeinschaft KR 806/13-1Helmholtz Gemeinschaft VH-VI-061U S National Science Foundation AST 07-07447, AST 06-07708Astronom

Long‐term impact of childhood selective dorsal rhizotomy on pain, fatigue, and function: a case–control study

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138232/1/dmcn13481_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138232/2/dmcn13481.pd

Poster 121: Properties of Wrist‐Worn Accelerometers in Individuals with Spinal Cord Injury

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147132/1/pmr2s173b.pd

Measures for the Assessment of Pain in Adults

Peer reviewedPublisher PD

Transient Effects of Sleep on Next-Day Pain and Fatigue in Older Adults With Symptomatic Osteoarthritis

Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.Peer reviewedPublisher PD

Fatigue predicts future reduced social participation, not reduced physical function or quality of life in people with systemic sclerosis

Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by a grant from the Patient Centered Outcomes Research Institute (PCORI; Poole/Khanna co-PIs) (Award CER-1310-08323 to J.L.P. and D.K.). The statements presented in this publication are solely the responsibility of the authors and do not necessarily represent the views of PCORI. Dr. Khanna’s work was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases at National Institutes of Health (K24-AR-063129)Peer reviewedPostprin

Fatigue and its Association with Social Participation, Functioning and Quality of Life in Systemic Sclerosis

Supported by the Patient-Centered Outcomes Research Institute (grant CER-1310-08323 to Drs. Poole and Khanna as co–principal investigators). Dr. Khanna’s work was supported by the NIH (National Institute of Arthritis and Musculoskeletal and Skin Diseases grant K24-AR-063129).Peer reviewedPostprin

The role of environmental distractions in the experience of fibrofog in real-world settings

The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. Supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the NIH (award K01‐AR‐064275; Principal Investigator, Dr. Kratz). The Michigan Institute for Clinical & Health Research (NIH award UL1‐TR‐002240) provided subject recruitment support through the UMHealthResearch.org website.Peer reviewedPublisher PD

Sleep disturbance as a moderator of the association between physical activity and later pain onset among American adults aged 50 and over : evidence from the Health and Retirement Study

Funding DW is supported by a Foundation Fellowship Versus Arthritis (Award Number: 21742). Contributors DW, HG, LMS, TJB, AK and GLD were involved in study conception and design, and advised on the statistical analysis plan and interpretation of the data. HG compiled the dataset and DW performed the statistical analysis. DW drafted the manuscript. HG, LMS, TJB, AK and GLD reviewed the manuscript, provided amendments and approved the final version. DW, HG and GLD had full access to study data and take responsibility for its accuracy and the integrity of the analysis. Data availability statement Data are available in a public, open access repository. The dataset used for this study was generated from data products publicly released by the Health and Retirement Study (HRS): https://hrs.isr.umich.edu. The HRS is sponsored by the National Institute on Ageing (grant number NIA U01AG009740).Peer reviewedPublisher PD

Healthâ Related Quality of Life Components in Children With Neonatal Brachial Plexus Palsy: A Qualitative Study

BackgroundCurrently, no published, validated patientâ reported outcome (PRO) measures of healthâ related quality of life (HRQOL) exist for use with neonatal brachial plexus palsy (NBPP). NBPP is a debilitating condition that occurs during the perinatal period, resulting in paralysis/paresis and loss of sensation in the affected arm. Commonly used NBPP measures are not comprehensive and do not fully account for clinically meaningful changes in function or progression of the disorder.ObjectiveTo evaluate important components of HRQOL for children with NBPP and identify where new PRO measures are needed.DesignEleven focus groups comprising children with NBPP (4), family members (6), and professional providers (1) to assess HRQOL.SettingBrachial plexus clinic.ParticipantsChildren with NBPP, their parents, and professional providers.Inclusion CriteriaChildren 7â 17 years old with NBPP; parents/caregivers at least 18 years of age; professionals with â ¥2 years’ experience providing NBPP clinical care; ability to read and speak English fluently.MethodsFocus group sessions were recorded, transcribed verbatim, and deidentified. Qualitative frequency analysis identified different aspects of HRQOL relevant to NBPP. This analysis expands on the groundedâ theory approach to qualitative analysis, including development of a domain framework, open and axial coding, selective coding, and descriptive analysis. The resulting HRQOL domain framework (and frequency analysis) was then compared to the domain framework for existing PRO measures (PROMIS and Neuroâ QoL) to identify components of HRQOL where new PRO measures are needed for NBPP.Main Outcome MeasuresNot applicable.ResultsAlthough many physical, social, and emotional health domains were captured by existing PRO measures, some significant NBPPâ specific topics emerged from qualitative analysisâ functionality, sensory, physical appearance, arm/hand compensation and preference, explaining functionality/appearance to others, and selfâ esteem and body image concerns.ConclusionsDevelopment of sensitive and specific measures capturing arm/hand function and body image would improve the clinical care of patients with NBPP.Level of EvidenceNot applicable.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146831/1/pmr2383.pd