Bulk gravitational field and dark radiation on the brane in dilatonic brane world

We discuss the connection between the dark radiation on the brane and the bulk gravitational field in a dilatonic brane world model proposed by Koyama and Takahashi where the exact solutions for the five dimensional cosmological perturbations can be obtained analytically. It is shown that the dark radiation perturbation is related to the non-normalizable Kaluza-Klein (KK) mode of the bulk perturbations. For the de Sitter brane in the anti-de Sitter bulk, the squared mass of this KK mode is $2 H^2$ where $H$ is the Hubble parameter on the brane. This mode is shown to be connected to the excitation of small black hole in the bulk in the long wavelength limit. The exact solution for an anisotropic stress on the brane induced by this KK mode is found, which plays an important role in the calculation of cosmic microwave background radiation anisotropies in the brane world.Comment: 11 page

Radionic Non-uniform Black Strings

Non-uniform black strings in the two-brane system are investigated using the effective action approach. It is shown that the radion acts as a non-trivial hair of the black strings. From the brane point of view, the black string appears as the deformed dilatonic black hole which becomes dilatonic black hole in the single brane limit and reduces to the Reissner-Nordstr\"om black hole in the close limit of two-branes. The stability of solutions is demonstrated using the catastrophe theory. From the bulk point of view, the black strings are proved to be non-uniform. Nevertheless, the zeroth law of black hole thermodynamics still holds.Comment: 9 pages, 6 figure

Brane-World Gravity

The observable universe could be a 1+3-surface (the "brane") embedded in a 1+3+\textit{d}-dimensional spacetime (the "bulk"), with Standard Model particles and fields trapped on the brane while gravity is free to access the bulk. At least one of the \textit{d} extra spatial dimensions could be very large relative to the Planck scale, which lowers the fundamental gravity scale, possibly even down to the electroweak ($\sim$ TeV) level. This revolutionary picture arises in the framework of recent developments in M theory. The 1+10-dimensional M theory encompasses the known 1+9-dimensional superstring theories, and is widely considered to be a promising potential route to quantum gravity. At low energies, gravity is localized at the brane and general relativity is recovered, but at high energies gravity "leaks" into the bulk, behaving in a truly higher-dimensional way. This introduces significant changes to gravitational dynamics and perturbations, with interesting and potentially testable implications for high-energy astrophysics, black holes, and cosmology. Brane-world models offer a phenomenological way to test some of the novel predictions and corrections to general relativity that are implied by M theory. This review analyzes the geometry, dynamics and perturbations of simple brane-world models for cosmology and astrophysics, mainly focusing on warped 5-dimensional brane-worlds based on the Randall--Sundrum models. We also cover the simplest brane-world models in which 4-dimensional gravity on the brane is modified at \emph{low} energies -- the 5-dimensional Dvali--Gabadadze--Porrati models. Then we discuss co-dimension two branes in 6-dimensional models.Comment: A major update of Living Reviews in Relativity 7:7 (2004) "Brane-World Gravity", 119 pages, 28 figures, the update contains new material on RS perturbations, including full numerical solutions of gravitational waves and scalar perturbations, on DGP models, and also on 6D models. A published version in Living Reviews in Relativit

Memory Immune Responses against Pandemic (H1N1) 2009 Influenza Virus Induced by a Whole Particle Vaccine in Cynomolgus Monkeys Carrying Mafa-A1*052∶02

We made an H1N1 vaccine candidate from a virus library consisting of 144 ( = 16 HA×9 NA) non-pathogenic influenza A viruses and examined its protective effects against a pandemic (2009) H1N1 strain using immunologically naïve cynomolgus macaques to exclude preexisting immunity and to employ a preclinical study since preexisting immunity in humans previously vaccinated or infected with influenza virus might make comparison of vaccine efficacy difficult. Furthermore, macaques carrying a major histocompatibility complex class I molecule, Mafa-A1*052∶02, were used to analyze peptide-specific CD8+ T cell responses. Sera of macaques immunized with an inactivated whole particle formulation without addition of an adjuvant showed higher neutralization titers against the vaccine strain A/Hokkaido/2/1981 (H1N1) than did sera of macaques immunized with a split formulation. Neutralization activities against the pandemic strain A/Narita/1/2009 (H1N1) in sera of macaques immunized twice with the split vaccine reached levels similar to those in sera of macaques immunized once with the whole particle vaccine. After inoculation with the pandemic virus, the virus was detected in nasal samples of unvaccinated macaques for 6 days after infection and for 2.67 days and 5.33 days on average in macaques vaccinated with the whole particle vaccine and the split vaccine, respectively. After the challenge infection, recall neutralizing antibody responses against the pandemic virus and CD8+ T cell responses specific for nucleoprotein peptide NP262-270 bound to Mafa-A1*052∶02 in macaques vaccinated with the whole particle vaccine were observed more promptly or more vigorously than those in macaques vaccinated with the split vaccine. These findings demonstrated that the vaccine derived from our virus library was effective for pandemic virus infection in macaques and that the whole particle vaccine conferred more effective memory and broader cross-reactive immune responses to macaques against pandemic influenza virus infection than did the split vaccine

An Exact Tunneling Solution in a Simple Realistic Landscape

We present an analytical solution for the tunneling process in a piecewise linear and quadratic potential which does not make use of the thin-wall approximation. A quadratic potential allows for smooth attachment of various slopes exiting into the final minimum of a realistic potential. Our tunneling solution thus serves as a realistic approximation to situations such as populating a landscape of slow-roll inflationary regions by tunneling, and it is valid for all regimes of the barrier parameters. We shortly comment on the inclusion of gravity.Comment: RevTeX 4.1, 4 pages, 5 figure