17 research outputs found
Studies toward Diazonamide A:Â Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure [ J. Am. Chem. Soc.
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Regioselektivität bei der 1,3-dipolaren Cycloaddition von Nitriloxiden mit N-(3,5-Dichlorphenyl)itaconimid
No full textA concise route to branched erythrono-gamma-lactones. Synthesis of the leaf-closing substance potassium ()-(2R,3R)-2,3,4-Trihydroxy-2-methylbutanoate
No full text© 2009 American Chemical SocietyA series of 1,2-dioxanes 3 were ring-opened with Co(SALEN)(2) to furnish lactol regioisomers 4 and 5 (86-99% yield). The lactols were oxidized to gamma-lactones 8 and 9 (72-96% yield) and deprotected to afford the 2-C- and 3-C-alkyl and aryl branched erythrono-gamma-lactones 1, 6, and 7 (65-94% yield), including the natural plant lactone (+/-)-2-C-d-methylerythrono-1,4-lactone 1. The latter compound was treated with aqueous potassium hydroxide to afford potassium (+/-)-(2R,3R)-2,3,4-trihydroxy-2-methylbutanoate 2, which is a leaf-closing substance of Leucaena leucocephalam.Daniel Sejer Pedersen, Tony V. Robinson, Dennis K. Taylor and Edward R. T. Tiekin
Enantioselective Construction of a Polyhydroxylated Pyrrolidine Skeleton from 3-Vinylaziridine-2-carboxylates: Synthesis of (+)-DMDP and a Potential Common Intermediate for (+)-Hyacinthacine A 1
No full textNitroxide-mediated polymerization of styrene and limonene in the framework of synthesis of potentially functional polymers using naturally occurring terpenes
No full textThe Role of Phosphate in a Multistep Enzymatic Reaction: Reactions of the Substrate and Intermediate in Pieces
No full textA Guide to Sonogashira Cross-Coupling Reactions: The Influence of Substituents in Aryl Bromides, Acetylenes, and Phosphinesand phosphines
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