日本人口腔癌患者におけるPD-L1およびPD-1の免疫組織学的評価

要約のみTohoku University高橋哲課

Western North Pacific Integrated Physical-Biogeochemical Ocean Observation Experiment (INBOX): Part 3. Mesoscale variability of dissolved oxygen concentrations observed by multiple floats during S1-INBOX

As part of the interdisciplinary project S1-INBOX (Western North Pacific Integrated Physical-Biogeochemical Ocean Observation Experiment conducted around the S1 biogeochemical mooring site), we used data from more than 18 floats and a biogeochemical mooring S1 (near 30° N, 145° E) to investigate temporal and spatial changes in the shallow oxygen maximum (SOM) associated with a mesoscale cyclonic eddy. On the northern edge of the cyclonic eddy, patches (linear dimensions of 20–40 km) with relatively high oxygen concentrations were observed around the SOM. The patterns of the oxygen concentrations reflected the fact that changes of the depths of the isopycnal surfaces were caused by small disturbances associated with the eddy structure along the eddy edge. The implication is that nutrient-rich water was supplied by upward isopycnal heaving at the edge of the eddy and contributed to the formation of the high-oxygen patches. As relatively high oxygen concentrations on the same isopycnal surfaces at greater depths were sometimes observed in the region downstream of the high-oxygen patches, we suggest that the patches were advected to the downstream region. The high-oxygen water seemed to extend into the eddy core from its edge. Ageostrophic secondary circulation around the edge of the eddy might have contributed to maintenance of the high oxygen concentrations in the eddy core, and these high oxygen concentrations may have been formed during spin-up of the eddy by heaving of isopycnal surfaces

Raman spectroscopic thermometer for carbonaceous material in chondrites

第6回極域科学シンポジウム[OA] 南極隕石11月16日（月）　国立国語研究所 2階 講

Western North Pacific Integrated Physical-Biogeochemical Ocean Observation Experiment (INBOX): Part 2. Biogeochemical responses to eddies and typhoons revealed from the S1 mooring and shipboard measurements

An interdisciplinary project called S1-INBOX (Western North Pacific Integrated PhysicalBiogeochemical Ocean Observation Experiment conducted around the S1 biogeochemical mooring site) was carried out during the summer of 2011 in the oligotrophic, subtropical North Pacific Ocean near biogeochemical mooring S1 (30° N, 145° E). Results from the S1 mooring during S1-INBOX revealed a large export flux at a depth of 200 m, a high chlorophyll a concentration in the deep chlorophyll maximum layer, and a high potential photochemical efficiency of photosystem II. These phenomena were associated with vertical uplift of isopycnal surfaces at the edge of a cyclonic eddy and a transition from the cyclonic eddy to an anticyclonic eddy. Shipboard biogeochemical surveys conducted during oligotrophic conditions in July 2011 revealed that the phytoplankton community in these waters was dominated by small species that are responsive to intermittent supplies of nutrients. Surface wind forcing because of Typhoons MA-ON and SONCA may have generated near-inertial oscillations. Diapycnal mixing associated with near-inertial waves was also related to high export fluxes, the indication being that propagation of near-inertial internal waves and subsequent mixing may have been important to biogeochemical phenomena during S1-INBOX