Role of lipids in molecular thermoadaptation mechanisms of seagrass Zostera marina

By using the combined approaches of microcalorimetric analysis and polarizing microscopy, the crystal-liquid crystal-isotropic melt phase transition of major phospholipids (phosphatidylcholine and phosphatidylethanolamine) and glycolipids (monogalactosyldiacylglycerol and digalactosyldiacylglycerol) isolated from marine seagrass Zostera marina were investigated. Here we discuss the results in view of the fatty acid structures of the lipids studied

ADJUVANT EFFECT OF TUBULAR IMMUNOSTIMULATING COMPLEXES MODIFIED BY ECHINOCHROME A, TOWARDS A PORE PROTEIN FROM YERSINIA PSEUDOTUBERCULOSIS

Abstract. We investigated immunogenic properties of vaccine constructs based on lipid-saponin tubular immunostimulating  complexes  (TI-complexes),  and  an  individual  antigen,  i.e.,  monomeric  and  trimeric forms of porin isolated from Yersinia pseudotuberculosis. An opportunity of enhanced immune response to TI-embedded porin was shown upon addition of echinochrome A (ECA) from sea urchin Scaphechinus mirabilis to TI-complexes. Immunization of mice with such a vaccine preparation results into a more intense specific humoral immune response to monomeric and trimeric forms of porin. (Med. Immunol., 2011, vol. 13, N 2-3, pp 139-144