20 research outputs found

    EPIDEMIOLOGICAL STUDY OF MAIN CLONES DISTRIBUTION GENOTYPE BEIJING OF MYCOBACTERIUM TUBERCULOSIS WITHIN IRKUTSK REGION

    Get PDF
    Aim. To estimate the dynamics changes in the population structure of the tuberculosis (ТВ) pathogen in the Irkutsk region by comparison of genotypes of M. tuberculosis from patients of different age groups. Materials and methods. 588 epidemiologically unrelated strains of M. tuberculosis isolates from 567 ТВ patients were characterized using 24-locus MIRU-VNTR typing. 160 strains belonged to patients of different age groups. 59 strains were isolated from the «young» people with ТВ who were bom after 1990 and 101 isolates from people who were born before 1955. Results. Two-thirds of the samples (427/567) were genotype Beijing with the dominance of two subtypes belonging to the modem epidemic clonal complexes CC1 and CC2. The high level of clustering profiles of CC1 and CC2 genotype Beijing in «older» and «young» patients in the Irkutsk region indicates the presence and active transmission of epidemic CC1 and CC2 subtypes over the past fifty years

    Heterogeneity of the interstellar diamond in the CV3 meteorite efremovka

    No full text
    Based on the heterogeneity in the contents and isotopic compositions of carbon, nitrogen, and rare gases found in different (in grain size) interstellar diamond fractions of the meteorite Efremovka, we discuss issues associated with the nature of the diamond, the distribution of the isotopic components of impurity chemical elements in it, and the kinetics of their release
    corecore