4 research outputs found
3D Hydrodynamical Simulations of Helium-ignited Double-degenerate White Dwarf Mergers
The origins of Type Ia supernovae (SNe Ia) are still debated. Some of the leading scenarios involve a double detonation in double white dwarf (WD) systems. In these scenarios, helium shell detonation occurs on top of a carbon-oxygen (CO) WD, which then drives the detonation of the CO core, producing an SN Ia. Extensive studies have been done on the possibility of a double helium detonation, following a dynamical helium mass-transfer phase onto a CO-WD. However, 3D self-consistent modeling of the double-WD system, the mass transfer, and the helium shell detonation have been little studied. Here we use 3D hydrodynamical simulations to explore this case in which a helium detonation occurs near the point of Roche lobe overflow of the donor WD and may lead to an SN Ia through the dynamically driven double-degenerate double-detonation (D6) mechanism. We find that the helium layer of the accreting primary WD does undergo a detonation, while the underlying CO core does not, leading to an extremely rapid and faint nova-like transient instead of a luminous SN Ia event. This failed core detonation suggests that D6 SNe Ia may be restricted to the most massive CO primary WDs. We highlight the nucleosynthesis of the long-lived radioisotope 44Ti during explosive helium burning, which may serve as a hallmark both of successful as well as failed D6 events, which subsequently detonate as classical double-degenerate mergers
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Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths
BACKGROUNDEvidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and prescription opioid safety. Data are needed on the effectiveness of a community-engaged intervention to reduce opioid-related overdose deaths through enhanced uptake of these practices.METHODSIn this community-level, cluster-randomized trial, we randomly assigned 67 communities in Kentucky, Massachusetts, New York, and Ohio to receive the intervention (34 communities) or a wait-list control (33 communities), stratified according to state. The trial was conducted within the context of both the coronavirus disease 2019 (Covid-19) pandemic and a national surge in the number of fentanyl-related overdose deaths. The trial groups were balanced within states according to urban or rural classification, previous overdose rate, and community population. The primary outcome was the number of opioid-related overdose deaths among community adults.RESULTSDuring the comparison period from July 2021 through June 2022, the population-averaged rates of opioid-related overdose deaths were similar in the intervention group and the control group (47.2 deaths per 100,000 population vs. 51.7 per 100,000 population), for an adjusted rate ratio of 0.91 (95% confidence interval, 0.76 to 1.09; P = 0.30). The effect of the intervention on the rate of opioid-related overdose deaths did not differ appreciably according to state, urban or rural category, age, sex, or race or ethnic group. Intervention communities implemented 615 evidence-based practice strategies from the 806 strategies selected by communities (254 involving overdose education and naloxone distribution, 256 involving the use of medications for opioid use disorder, and 105 involving prescription opioid safety). Of these evidence-based practice strategies, only 235 (38%) had been initiated by the start of the comparison year.CONCLUSIONSIn this 12-month multimodal intervention trial involving community coalitions in the deployment of evidence-based practices to reduce opioid overdose deaths, death rates were similar in the intervention group and the control group in the context of the Covid-19 pandemic and the fentanyl-related overdose epidemic. (Funded by the National Institutes of Health; HCS ClinicalTrials.gov number, NCT04111939.)