Interaction of powdery Al, Zr and Ti with atmospheric nitrogen and subsequent nitride formation under the metal powder combustion in air

The combustion process in air for aluminum nanopowders (nAl), micron-sized powders of aluminum (Al), titanium (Ti) and zirconium (Zr) was accompanied by the predominant reaction of the metals with N2 and the subsequent stabilization of the nitride phases (from 38wt.% of ZrN for Zr combustion to 72wt.% of AlN for nAl combustion) in the condensed combustion products (CCP). The combustion process, composition and structure of CCP of nAl, Al, Ti, and Zr were studied. Scanning electronic microscopy (SEM), X-ray diffraction (XRD), energy dispersive (X-ray) spectroscopy (EDX), and chemical analysis were performed on both initial powders and CCP. The combustion mechanism for the studied metal powders was experimentally proved. The formation of a large amount of non-equilibrium products (AlN, ZrN, TiN) instead of oxides in air is the special feature of the above mentioned experimental conditions. Nitride formation in air was defined by high temperatures and high burning rates du ring combustion of powdery Al, Ti and Zr

Expert Council: promising areas of systemic enzyme therapy in gynecology

Yu.E. Dobrokhotova1, A.A. Khryanin2, E.V. Shikh3, L.Yu. Karakhalis4, I.M. Ordiyants5, E.A. Kogan1, A.V. Yakimova2, I.N. Korotkikh6, N.I. Kokhno7 1Pirogov Russian National Research Medical University, Moscow, Russian Federation 2Novosibirsk State Medical University, Novosibirsk, Russian Federation 3I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation 4Russian University of Peoples' Friendship, Moscow, Russian Federation 5Kuban State Medical University, Krasnodar, Russian Federation 6N.N. Burdenko Voronezh State Medical University, Voronezh, Russian Federation 7LLC “Center of Reproduction and Genetics”, Moscow, Russian Federation The interdisciplinary scientific and practical conference «Expert Council: promising areas of systemic enzyme therapy (SET) in gynecology» under the auspices of the National Association of Obstetricians-Gynecologists and Reproductologists "Women's Health" was held in Moscow on December 02, 2022. The conference brought together specialists from multiple Russian regions. The development of effective treatment algorithms for infection-caused inflammatory diseases in the practices of obstetricians and gynecologists remains relevant in view of the continuous growth of antimicrobial resistance underpinned both by the irrational use of antibiotics and the biofilm-forming ability of infectious agents. The speakers shared their experience of using systemic enzyme therapy (SET) in the combination treatment of inflammatory diseases in obstetric and gynecological practice, as well as in the prevention of fibrous and adhesive complications of pelvic inflammatory diseases (PID) and gynecologic surgeries. It was pointed out that systemic enzyme therapy should be recognized as a justified component of the combination PID treatment which helps to reduce the duration and severity of symptoms due to its proven immunomodulatory, fibrinolytic and antiplatelet effects. The use of SET drugs reduces the duration of all stages of reparative regeneration along with tamping down the inflammatory response. The Expert Council Resolution provides recommendations on using SET in gynecology. Keywords: proteolytic enzymes, pelvic inflammatory diseases, endometritis, adhesions, antibiotic resistance, systemic enzyme therapy. For citation: Dobrokhotova Yu.E., Khryanin A.A., Shikh E.V. et al. Expert Council: promising areas of systemic enzyme therapy in gynecology. Russian Journal of Woman and Child Health. 2023;6(2):149–156 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-149-156. </p

Total flavonoids in crataegus «Flowers with leaves» raw material of Russian Flora

The total flavonoid content of various species of Crataegus novel raw material- «flowers with leaves» was conducted to a comparative study in order to identify the possibility of co-harvesting material from different species. 27 samples of 6 pharmacopoeial and 7 nonpharmacopoeial Crataegus species obtained from the Biological Collections of VILAR, Tsitsin Main Botanical Garden RAS, Kuzbass, Penza and Stavropol Botanical Gardens, Altai Territory, Voronezh region, Kemerovo and Moscow harvested in Russian Federation were analyzed. Spectrophotometric assay based on aluminium complex formation was used for determination of total flavonoid expressed as hyperoside. The fractional composition of the raw material (percentage of leaves and stems) and its influence on the content of flavonoids was studied. The total flavonoids expressed as hyperoside of the raw material "flowers with leaves" of pharmacopoeial Crataegus species ranged from 1.40±0.05% (C. chlorocarpa) to 2.20±0.11% (C. monogyna), nonpharmacopeal species - from 1.21±0.11% (C. maximowiczii) to 2.21±0.09% (C. ambigua). The average quantity was 1.65%. The total flavonoid values of non-pharmacopoeial species raw material were comparable with pharmacopoeial species thus it allows to consider them promising for further study and use of their parts for medical purpose. © Altai State University. All rights reserved