10 research outputs found

    Inhibitory Effects of Roquefortine on Hepatic Cytochromes P450

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    Roquefortine E, a diketopiperazine from an Australian isolate of Gymnoascus reessii

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    The new isoprenylated diketopiperazine roquefortine E (6) has been isolated from an Australian soil isolate of the ascomycete Gymnoascus reessii. The known fungal metabolite roquefortine C (1) was also recovered as the major antibacterial principle, and all structures were assigned by detailed spectroscopic analysis

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