Fusion of morphological data obtained by coronary computed tomography angiography with quantitative echocardiographic data on regional myocardial function

Background: Three-dimensional (3D) fusion of morphological data obtained by coronary computed tomography angiography (CCTA) with functional data from resting and stress echocardiography could potentially provide additional information compared to examination results analyzed separately and increase the diagnostic and prognostic value of non-invasive imaging in patients with suspected coronary artery disease (CAD). Using vendor-independent software developed in our institution, we aimed to assess the feasibility and reproducibility of 3D fusion of morphological CCTA data with echocardiographic data regarding regional myocardial function. Methods: Thirty patients with suspected CAD underwent CCTA and resting transthoracic echocardiography. From CCTA we obtained 3D reconstructions of coronary arteries and left ventricle (LV). Offline speckle-tracking analysis of the echocardiographic images provided parametric maps depicting myocardial longitudinal strain in 17 segments of the LV. Using our software, 3 independent investigators fused echocardiographic maps with CCTA reconstruc­tions in all patients. Based on the obtained fused models, each segment of the LV was assigned to one of the major coronary artery branches. Results: Mean time necessary for data fusion was 65 ± 7 s. Complete agreement between independent investigators in assignment of LV segments to coronary branches was obtained in 94% of the segments. The average coefficient of agreement (kappa) between the investigators was 0.950 and the intra-class correlation coefficient was 0.9329 (95% CI 0.9227–0.9420). Conclusions: Three-dimensional fusion of morphological CCTA data with quantitative echocardiographic data on regional myocardial function is feasible and allows highly repro­ducible assignment of myocardial segments to coronary artery branches

Dorosła z Tetralogią Fallota, anomalią odejścia tętnicy wieńcowej, niescaleniem lewej komory, ubytkiem w przegrodzie międzyprzedsionkowej i nawracającym zwężeniem w drodze odpływu prawej komory

Advances in therapeutical possibilities for patients with complex congenital heart defects are unquestionable. Nonetheless, it is still probable to encounter unique challenges. The study presents a case of a symptomatic 25-year-old female patient with uncorrected Tetralogy of Fallot who has never been qualified for surgery due to an unusual constellation of cardiac congenital comorbidities: anomalous coronary artery origin and non-compaction of the left ventricle.Postępy w możliwościach terapeutycznych dla pacjentów ze złożonymi wrodzonymi wadami serca są nie do zakwestionowania. Jednakże wciąż istnieje prawdopodobieństwo napotkania wyjątkowych wyzwań. W niniejszej pracy zaprezentowano przypadek objawowej 25-letniej pacjentki z nieskorygowaną Tetralogią Fallota, która nigdy nie była zakwalifikowana do operacji z powodu unikatowej konstelacji wrodzonych schorzeń serca: anomalii odejścia tętnicy wieńcowej i kardiomiopatii z niescalenia lewej komory

Olbrzymi tętniak rzekomy drogi wypływu z prawej komory: postępowanie interwencyjne i komplikacje

We report a case of a 19-year-old patient with double outlet right ventricle (RV) and recurrent giant RV outflow tract pseudoaneurysm, after multiple redo surgery. The patient underwent implantation of a 10 mm Amplatzer Septal Occluder to close the pseudoaneurysm. Postinterventional echocardiography revealed dislocation of the device into the cavity of the pseudoaneurysm. Consecutive computed tomography enabled three-dimensional measurements of the pseudoaneurysmand its orifice and resulted in implantation of a 20 mm occluder

Experimental Validation of Numerical Methods of MRE Simulations

This paper deals with the development of magnetoactive elastomers (MREs) based on the carbonyl iron particles-filled polyurethane resin. Their stiffness can be changed easily by magnetic field. Such a property can be useful in construction of active vibration damping structural elements. For the needs of numerical modelling methods validation the elementary case of the two magnetic particles was investigated experimentally. Special “macro samples” were prepared with pairs of ferromagnetic particles of spherical shape of diameter of 12.7 mm. They provided easy observations and measurements. The gap distance between particles was established on the level of ¼ of the diameter. After application of the magnetic field particles started to attract each other like magnetic dipoles. The mutual displacement of the dipoles was recorded in function of the magnetic field intensity, which was varied in the range100÷300 [mT]. The deformation field was also obtained from the digital image processing (DIC). Then the experiment was simulated numerically with the use of the 3D FEM models. The dipoles were loaded by forces which were increased gradually until displacements reached values that were measured experimentally. Calculations were performed on the MSC Patran-MARC platform. The Neo-Hookean material model was used to describe properties of the resin matrix. Magneto-mechanical coupling was taken into consideration with the use of an iterative method. The results of calculations were compared with the experimental results. The validation of the base modelling concept was successfully completed.</jats:p