A new 3-day standardized eyeblink conditioning protocol to assess extinction learning from infancy to adulthood

Associative learning can be observed from the neonatal period onward, providing opportunities to examine changes in basic learning and memory abilities. One method that is suitable to study associative learning is classical eyeblink conditioning (EBC) which is dependent on the cerebellum. Extinction learning can be systematically investigated in this paradigm by varying the context during learning and extinction. Because of methodological difficulties and ethical challenges, no studies have compared extinction learning using EBC across human development. Our goal was to test feasibility of a 3-day delay EBC paradigm that can be used from infancy to adulthood. Acceptance/safety was tested especially for infancy by investigating attrition rates and parental report on infant wellbeing. On a paradigm side, we tested if the paradigm leads to successful acquisition and extinction. An air puff served as unconditional stimulus (US) and a tone as conditional stimulus (CS). On day 1 during acquisition, participants received 36 US–CS pairings in context A. On day 2, participants received 12 acquisition trials in context A to consolidate association learning, followed by 48 extinction trials (tone alone presentations) in context B. Renewal was assessed on day 3 and incorporated 12 CS alone trials presented in both the acquisition context and the extinction context. Eyeblink responses were videotaped and coded offline. The protocol was tested with 12–36-months-old infants ($\it N$ = 72), adolescents ($\it N$ = 8), and adults ($\it N$ = 8). Concerning the acceptance/safety side, attrition ranged from 21 to 58% in infant samples due to the complex preparation of the children for the paradigm. However, attrition is equal to or lower than other infant learning paradigms. Parents of infant samples were very interested in the paradigm and reported low levels of infant stress, exhaustion, and negative feelings during the sessions. Data quality was very high, and no participant had to be excluded because of insufficient data. Concerning the paradigm side, participants showed successful acquisition and extinction as a group. The procedure is ethically sound, feasible, tolerated by many infants, and acceptable among parents. The data show successful acquisition and extinction rates, making the paradigm a valuable tool for investigating developmental changes in extinction learning over the lifespan

State-dependent memory in infants

Why do infants remember some things and not others? Human infants frequently cycle through different states such as calm attentiveness, wakeful activity, and crying. Given that cognitive processes do not occur in isolation, such fluctuations in internal state might influence memory processing. In the present experiment, declarative memory in 9-month-old infants ($\it N$ = 96) was heavily state dependent. Infants exhibited excellent retention of a deferred imitation task after a 15-min delay if their state at encoding was identical to their state at retrieval (e.g., calm). Infants failed to exhibit retention if their state at encoding was different from their state at retrieval (e.g., calm vs. animated). Infant memory processing depends on internal cues

Quality of mother-child interaction before, during, and after smartphone use

Studies have demonstrated that parents often exhibit a still face while silently reading their cell phones when responding to texts. Such disruptions to parent-child interactions have been observed during parental media use such as texting and these disruptions have been termed technoference. In the present study, we explored changes to mother-child interactions that occur before, during and after interruptions due to texting using an adapted naturalistic still face paradigm. Specifically, we examined the effect of an interruption due to either maternal smartphone use or use of an analog medium on maternal interaction quality with their 20- to 22-month-old children. Mother-child interactions during free play were interrupted for 2 min by asking the mothers to fill out a questionnaire either (a) by typing on the smartphone (smartphone group) or (b) on paper with a pen (paper-pencil group). Interactional quality was compared between free-play and interruption phases and to a no-interruption control group. Mixed ANOVA across phase and condition indicated that maternal responsiveness and pedagogical behavior decreased during the interruption phase for both the interruption groups (smartphone and paper-and-pencil) but not for the no-interruption group. Children also increased their positive bids for attention during the paper-and-pencil and the smartphone conditions relative to the no-interruption control. These findings are consistent with a large body of research on the still-face paradigm and with a recent study demonstrating that smartphone interruptions decreased parenting quality. The present study, however, connects these lines of research showing the many everyday disruptions to parent-child interactions are likely to decrease parenting quality and that toddlers are likely to detect and attempt to repair such interruptions