The role playing by social media in COVID-19 to exacerbate anxiety and depression among Pakistani community

Introduction: The purpose of the worldwide lockdown was to impede the spread of this virus via social distancing. WHO detected symptoms like anxiety, stress, fear which have affected people’s psychology across the globe due to loneliness, substance abuse, depression and constant fear?  With the surge of information regarding COVID-19 on social media (myths and beliefs), it certainly played a major role for communities’ psychology all around the globe. Methods: A cross sectional study design was chosen with convenient sampling size of 800 via online. Questionnaire shared through online social media platforms. Statistical analysis was done through SPSS version 21 and responses were taken as frequencies, percentages and chi-square test. Results:  there was a significant association between highly educated peoples and social media usage with p-value less than 0.000 suggestive of myths generating decline of mental health.  Conclusion: COVID-19 information available over social media was used by everyone and considered as authentic. Therefore, control measures and legislation should be applied on them to restrict the ambiguity.  Key-words:  Social media; COVID-19; Myths; life worth; save humanity; Attitude;

The knowledge regarding Breast Cancer, its risk factors, and screening practices among women from Islamabad, Pakistan

Introduction: Breast Cancer is the rising Public health problem of the world. Pakistan is bearing a high disease burden not only in Asian countries but in the whole world. Pakistan ranks highest in Breast cancer and accounts for almost 34.6%of female cancers. The incidence of the disease in Asian countries is quite different from that in Western countries regarding age i.e. (40-50 years.) while (60-70 years) in Western countries. This study was based on assessing the knowledge regarding breast cancer, risk factors, and screening practices to determine the barriers in the path of the community to seek medical care.Materials and Methods: A cross-sectional study was done between October to December 2019 on 310 females participants of ages from 25 to 70 years, residents of Islamabad, the capital of Pakistan, and knowledge was assessed by applying a self-responding questionnaire.Results: Using SPSS version 23 and chi-square tests, the results showed that 87.7% of participants knew about the prevalence of Breast Cancer. Whereas, 90.3% of the females with the disease are not aware of their illness and show a strong association (p-value is less than 0.05) between knowledge regarding breast cancer and screening tests. Conclusion: The study concluded that 90% of socio-cultural barriers are in the path of access to medical facilities and 90% of participants believed that the non-availability of female doctors in health facilities is a big barrier to access to health. Access to medical facilities should be made easy by promoting health education and removing the fear of results, making small health facility units. &nbsp

Difficulty Index, Discrimination Index and Distractor Efficiency in Multiple Choice Questions

Objective: Our first objective was to evaluate the quality of MCQs by analyzing difficulty index, discrimination index and distractor efficiency. Our second objective was to find out the association of MCQs having good difficulty and discrimination indices with distractor efficiency.Methodology: This cross-sectional study was conducted at department of Pathology, Islamabad medical and dental college. Midterm paper comprising of total 65 MCQs was assessed for difficulty index (DIF), discrimination index (DI) and distractor efficiency (DE). Data was entered in Microsoft Excel 2010 and SPSS 21. Quantitative variables were expressed as mean±SD. Qualitative variables were written as number and percentage. Independent t-test was applied to find out the association of DIF and DI with DE.Results: According to DIF, out of total 65, 53(81%) MCQs were in acceptable category, only 1(2%) MCQ was too difficult and 11(17%) were too easy. Regarding DI, total 34(62%) MCQs showed excellent discrimination tendency to distinguish low and high performer students. While 15(23%), 5(8%) and 11(17%) MCQs demonstrated good, acceptable and poor discrimination ability respectively. Out of total 260 distractors, 72% were functional and only 28% were non-functional. Total 16(25%) MCQs had zero non-functional distractor (NFDs), while 30(46%) and 16(25%) MCQs had 1 and 2 NFDs respectively. Only 3(5%) MCQs were with 3 or more NFDs. DE was significantly more (100%) in 1 difficult item as compared to 11 easy items in which DE was less (36.33%). However, DE in MCQs having poor and good DI was almost same.Conclusion: In this paper of Pathology, large number of MCQs have acceptable level of DIF (81%) and DI (83%). Distractor efficiency related to presence of zero or 1 NFD is 71%. Through item analysis, standardized MCQs having average DIF, high discrimination power with large number of functioning distractors can be developed. Thus it is an effective way to improve the validity of examination and to efficiently assess the student performance

Development and Characterization of Chitosan and Chondroitin Sulfate Based Hydrogels Enriched with Garlic Extract for Potential Wound Healing/Skin Regeneration Applications

Hydrogels can provide instant relief to pain and facilitate the fast recovery of wounds. Currently, the incorporation of medicinal herbs/plants in polymer matrix is being investigated due to their anti-bacterial and wound healing properties. Herein, we investigated the novel combination of chitosan (CS) and chondroitin sulfate (CHI) to synthesize hydrogels through freeze gelation process and enriched it with garlic (Gar) by soaking the hydrogels in garlic juice for faster wound healing and resistance to microbial growth at the wound surface. The synthesized hydrogels were characterized via Fourier-transform infrared spectroscopy (FTIR), which confirmed the presence of relevant functional groups. The scanning electron microscopy (SEM) images exhibited the porous structure of the hydrogels, which is useful for the sustained release of Gar from the hydrogels. The synthesized hydrogels showed significant inhibition zones against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Furthermore, cell culture studies confirmed the cyto-compatibility of the synthesized hydrogels. Thus, the novel hydrogels presented in this study can offer an antibacterial effect during wound healing and promote tissue regeneration