63 research outputs found

    High Resolution Simultaneous Measurements of Airborne Radionuclides at Sub-regional Sampling Points by Ultra Low Background Gamma Spectrometry

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    金沢大学環日本海域環境研究センター地球環境計測研究部門Promoting Environmental Pesearch in Pan-Japan Sea Area : Young Researchers\u27 Network, Schedule: March 8-10,2006,Kanazawa Excel Hotel Tokyu, Japan, Organized by: Kanazawa University 21st-Century COE Program, Environmental Monitoring and Prediction of Long- & Short- Term Dynamics of Pan-Japan Sea Area ; IICRC(Ishikawa International Cooperation Research Centre), Sponsors : Japan Sea Research ; UNU-IAS(United Nations University Institute of Advanced Studies)+Ishikawa Prefecture Government ; City of Kanazaw

    High resolution simultaneous measurements of airborne radionuclides

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    金沢大学大学院自然科学研究科場所:金沢大学自然科学研究科図書館棟1階,講演会場:図書館棟1階 大会議室,ポスター会場:図書館棟1階12会議室,主催・共催:文部科学省21世紀COE「環日本海域の環境計測と長期・短期変動予測」, 大気環境学会, 金沢大学工学

    High resolution simultaneous measurements of airborne radionuclides

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    金沢大学大学院自然科学研究科場所:東京大学弥生講堂,共催:文部科学省21世紀COE「環日本海域の環境計測と長期・短期変動予測」,大気環境学

    CD14+monocytes are vulnerable and functionally impaired under ER stress in patients with type 2 diabetes

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    金沢大学医薬保健研究域医学系OBJECTIVE - Although patients with diabetes suffer from increased infections and a higher incidence of cancer due to impaired immune function, details on diabetes-induced decrease in immunity are lacking. We assessed how immune-mediating peripheral blood mononuclear cells (PBMCs) are affected in diabetes. RESEARCH DESIGN AND METHODS - From 33 patients with type 2 diabetes and 28 healthy volunteers, we obtained PBMCs and investigated their susceptibility to apoptosis and functional alteration. RESULTS - In a subpopulation of PBMCs, monocytes derived from patients with diabetes were more susceptible to apoptosis than monocytes from healthy volunteers. Monocytes from patients with diabetes had decreased phagocytotic activity and were less responsive to Toll-like receptor (TLR) ligands, although the expression of TLRs did not differ significantly between the two groups. Furthermore, monocytes from patients with diabetes had a distinctly different gene expression profile compared with monocytes from normal volunteers as assessed with DNA microarray analysis. Specifically, quantitative real-time detection PCR measurements showed an elevated expression of the markers of endoplasmic reticulum (ER) stress in diabetic monocytes, and electron microscopic examination of monocytes revealed morphologic alterations in the ER of cells derived from patients with diabetes. Consistently, the ER stress inducer tunicamycin increased apoptosis of otherwise healthy monocytes and attenuated the proinflammatory responses to TLR ligands. CONCLUSIONS - These data suggest that monocytes comprise a substantially impaired subpopulation of PBMCs in patients with diabetes and that ER stress is involved in these pathologic changes mechanistically. This implies that the affected monocytes should be investigated further to better understand diabetic immunity. © 2010 by the American Diabetes Association

    放射能を用いた大気中における物質の輸送過程に関する研究

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    Measurements of short-lived cosmogenic nuclides in rain samples

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    金沢大学自然計測応用研究センター自然計測研究部門金沢大学理学部Extremely low activity levels of cosmic ray induced nuclides have been measured in freshly precipitated rainwater by quick chemical separation coupled with ultra low background gamma-spectrometry. The nuclides detected were 38S (T1/2 = 2.83 h)-38Cl (37.2 m), 39Cl (55.6 m), 24Na (14.96 h), 28Mg (20.9 h), 7Be (53.3 d) and 22Na (2.602 y). The number of atoms in rain water were evaluated to be ranging from 400-1900 l-1 for 39Cl (n = 6, mean: 1200), 30-1500 l-1 for 24Na (n = 16, mean: 520), 80-600 l-1 for 28Mg (n = 13, mean: 260), 1·106-4·107 l-17Be (n = 16, mean: 7·106) and 2·10 3-1·105 l-1 for 22Na (n = 9, mean: 2·104). Measurements of activity levels and activity ratios of short-lived cosmic-ray induced short-lived nuclides will open new method to understand atmospheric processes occurred at the altitude of rain cloud. © 2006 Akadémiai Kiadó

    6.EMEA International Symposium in Kanazawa, Japan

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    The EMEA Project, Kanazawa UniversityProject Number 14404021, Peport of Research Project ; Grant-in-Aid for Scientific Research(B)(2), from April 2002 to March 2006, Edited by Muramoto,Ken-ichiroKamata, NaotoKawanishi, TakuyaKubo, MamoruLiu, JiyuanLee, Kyu-Sung , 人工衛星データ活用のための東アジアの植生調査、課題番号14404021, 平成14年度~平成17年度科学研究費補助金, 基盤研究(B)(2)研究成果報告書, 研究代表者:村本, 健一郎, 金沢大学自然科学研究科教

    Activities of the EMEA project during 1999-2005

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    金沢大学大学院自然科学研究科The EMEA Project, Kanazawa University2005 International Symposium on Environmental Mornitoring in East Asia -Remote Sensing and Forests-,Hosted The EMEA Project, Kanazawa University 21st=Century COE Program -Environmental Monitoring and Predicition of Long- and Short- Term Dynamics of Pan-Japan Sea Area- ,予稿集, EMEA 2005 in Kanazawa, 国際学術研究公開シンポジウム『東アジアの環境モニタリング』-リモートセンシングと森林-,年月日:200511月28日~29日, 場所:KKRホテル金沢, 金沢大学自然科学研究科, 主催:金沢大学EMEAプロジェクト, 共催:金沢大学21世紀COEプログラム「環日本海域の環境変動と長期・短期変動予測

    Mass transportation monitored by trace level radioactivity

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    金沢大学大学院自然科学研究科場所:金沢大学自然科学研究科図書館棟1階,講演会場:図書館棟1階 大会議室,ポスター会場:図書館棟1階12会議室,主催・共催:文部科学省21世紀COE「環日本海域の環境計測と長期・短期変動予測」, 大気環境学会, 金沢大学工学
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