Fractal Format for Bitmap Images

The conception of proposed recording format is the example of the theoretical and practical application of the FBS method, which was precisely described in thesis [18,19,20]. The foundation of the presented recording format is the use of a new method of fractal basis splines (FB-splines), which allows the reconstruction of complex geometric structures with the properties of fractals. Fractral basis splines method is based on the use of non-local characteristics to describe the interpolation nodes. With that the one-parameter family of fractal curves is used as the basic approximating elements

Ways of Selecting Internal Patterns in Multilayer Perceptron Network

Creating and later learning one-way neural networks depends on many factors. Selecting many of them has estimated and experimental character. The suggested method is the Allows weakness of the influence of the not optimal choice of the net structure, also speed and momentum values are less influential in classic Back then Propagation Method. There are few modes of choosing elements to use in Followed algorithm

Blood pressure in children and adolescents - some aspects of measurements interpretation

This work presents new possibilities for interpreting blood pressure measurements of children and adolescents with the use of Internet. A dynamic web site allows for such interpreting and archiving blood pressure measurements in developmental age. Stored measurements results can become a basis for national pressure norm considering specificity of development of Polish children and adolescents. The interpretation system of blood pressure measurements in developmental age can be used both at school and hom

Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice

Aims/hypothesis: The receptor for AGEs (RAGE) is linked to proinflammatory pathology in a range of tissues. The objective of this study was to assess the potential modulatory role of RAGE in diabetic retinopathy. Methods: Diabetes was induced in wild-type (WT) and Rage mice (also known as Ager mice) using streptozotocin while non-diabetic control mice received saline. For all groups, blood glucose, HbA and retinal levels of methylglyoxal (MG) were evaluated up to 24\ua0weeks post diabetes induction. After mice were killed, retinal glia and microglial activation, vasopermeability, leucostasis and degenerative microvasculature changes were determined. Results: Retinal expression of RAGE in WT diabetic mice was increased after 12\ua0weeks (p < 0.01) but not after 24\ua0weeks. Rage mice showed comparable diabetes but accumulated less MG and this corresponded to enhanced activity of the MG-detoxifying enzyme glyoxalase I in their retina when compared with WT mice. Diabetic Rage mice showed significantly less vasopermeability, leucostasis and microglial activation (p < 0.05–0.001). Rage mice were also protected against diabetes-related retinal acellular capillary formation (p < 0.001) but not against pericyte loss. Conclusions/interpretation: Rage in diabetic mice is protective against many retinopathic lesions, especially those related to innate immune responses. Inhibition of RAGE could be a therapeutic option to prevent diabetic retinopathy