14 research outputs found
The Directional Dependence of the Lunar Cherenkov Technique for UHE Neutrino Detection
The LUNASKA (Lunar UHE Neutrino Astrophysics with the Square Kilometre Array)
project is a theoretical and experimental project developing the lunar
Cherenkov technique for the next generation of giant radio-telescope arrays.
This contribution presents our simulation results on the directional dependence
of the technique for UHE neutrino detection. In particular, these indicate that
both the instantaneous sensitivities and time-integrated limits from lunar
Cherenkov experiments such as those at Parkes, Goldstone, Kalyazin and ATCA are
highly anisotropic. We study the regions of the sky which have not been probed
by either these or other experiments, and present the expected sky coverage of
future experiments with the SKA. Our results show how the sensitivity of Lunar
Cherenkov observations to potential astrophysical sources of UHE particles may
be maximised by choosing appropriate observations dates and antenna-beam
pointing positions.Comment: 4 pages, 4 figures, presented at ARENA 2008, Rome, Ital
Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up. Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections. Conclusions: After 100 years since the first Hartmann's procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment's choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception