Design Support of Transportation Routing for a Multi Layered Factory

Recently, it becomes important to improve transportation capability to attain high productivity in manufacturing. One of the necessary schemes to attain the purpose is that the floor layout is initially to be optimized. After the floor layout is determined, reasonable equipment position for transportation is decided. Then the design of the transportation route is to be determined. In this paper, design support system for transportation routing, based on agent method is proposed. To optimize the transportation route, the working space by the side of the equipment is to be prepared. Starting from given floor layout of a three layered factory, an appropriate transportation route is pursuit using Ant algorithm. To check the applicability of the proposed method, case studies are carried out under various constraints and objective functions, and its effects were verified

持続的腎代替療法におけるメシル酸ナファモスタットの血中動態

Continuous renal replacement therapy (CRRT) is the preferred dialysis modality in critical care settings for patients with hemodynamic instability. Nafamostat mesylate (NM) is an anticoagulant commonly used (mainly in Japan) during CRRT in patients with high bleeding risk. In this study, we evaluated the pharmacokinetics of NM during CRRT. Patients undergoing CRRT therapy and using NM as the anticoagulant in the intensive care unit were enrolled in the study. Blood was collected from the CRRT circuit just after blood removal, just before and after the membrane for CRRT, and from the filtrates after the membrane. NM concentrations were measured using high-performance liquid chromatography. NM was detected in the intracorporeal circulation during CRRT in some cases, and liver enzymes were severely elevated in almost all of the cases. Coagulation time was prolonged even before the initiation of NM administration in these cases and may be associated with liver damage. This study suggests that NM dosage should take into account liver damage assessed by elevated liver enzymes.博士（医学）・乙第1531号・令和5年3月15

Global Zero Emission Scenario: Role of Innovative Technologies

AbstractThis study investigated a zero emission scenario with following two originalities compared to various existing studies. One is that we based on A1T society of SRES (Special Report on Emissions Scenario) of IPCC (Intergovernmental Panel on Climate Change) compared to existing studies on those of B1 or B2. The second one is that various innovative and radical technologies were considered and incorporated, such as biomass energy with CCS (BECCS), and advanced nuclear technologies including hydrogen or synfuel production. We applied a global modeling, whose energies, materials, and biomass and foods supply costs were minimized by linear programing with time horizon up to 2150. We found following features of energy supply structure in A1T scenario. Since the electric demand in A1T scenario in 2100 is two times larger than the others, 1) renewable energy which solely produce electricity, nuclear, and fossil energy with CCS (FECCS) especially coal are main sources of electricity, 2) renewable which can supply heat, namely BECCS and geothermal, satisfies the sector, and 3) hydrogen from coal is introduced in transport sector. It can be concluded that the zero emission energy systems with global economic growth will be possible, by development and deployment of ambitious advanced energy technologies

Coincidence between transcriptome analyses on different microarray platforms using a parametric framework

A parametric framework for the analysis of transcriptome data is demonstrated to yield coincident results when applied to data acquired using two different microarray platforms. Discrepancies among transcriptome studies are frequently reported, casting doubt on the reliability of collected data. The inconsistency among observations can be largely attributed to differences among the analytical frameworks employed for data analysis. The existing frameworks normalizes data against a standard determined from the data to be analyzed. In the present study, a parametric framework based on a strict model for normalization is applied to data acquired using an in-house printed chip and GeneChip. The framework is based on a common statistical characteristic of microarray data, and each data is normalized on the basis of a linear relationship with this model. In the proposed framework, the expressional changes observed and genes selected are coincident between platforms, achieving superior universality of data compared to other methods

Crystal structure and magnetic properties of EuZrO₃ solid solutions

It is theoretically proposed that perovskite-type EuZrO₃ becomes a ferromagnet when the lattice volume is increased or the structure is changed from orthorhombic to cubic in contrast to the fact that the stable phase of EuZrO₃, the structure of which is orthorhombic, is antiferromagnetic. To investigate the change in crystal structure and magnetic properties of EuZrO₃ with the variation of lattice volume, we have synthesized polycrystals of solid solutions AxEu₁−xZrO₃ (A = Ba, Ca, Sr); Eu²⁺ is substituted by group 2 elements with different ionic radius to realize the change in lattice volume and crystal structure of EuZrO₃. The stable magnetic structure of EuZrO₃ solid solutions is tuned with the change of lattice volume. In particular, the ferromagnetic state is stabilized by the increase in lattice volume, which experimentally verifies the prediction by the first-principles calculations. Furthermore, this phenomenon is explainable in terms of the competition between ferromagnetic and antiferromagnetic interactions that is highly related to the volume variation and the rotation of ZrO₆ octahedron. The present results indicate that the magnetic structure can be systematically tuned by controlling the chemical pressure in solid solutions

FPGA Implementation of Hierarchical Subcarrier Rate and Distribution Matching for up to 1.032 Tb/s or 262144-QAM

A novel hierarchical subcarrier rate and distribution matching has been implemented in an FPGA at 1.032 Tb/s. The implemented subsystem achieves seamless data flow among subcarriers at a resolution < 0.01 bit per channel use

MOIRCS Deep Survey. VII: NIR Morphologies of Star-forming Galaxies at Redshift z~1

We investigate rest-frame near-infrared (NIR) morphologies of a sample of 139 galaxies with M_{s} >= 1 x 10^{10} M_{sun} at z=0.8-1.2 in the GOODS-North field using our deep NIR imaging data (MOIRCS Deep Survey, MODS). We focus on Luminous Infrared Galaxies (LIRGs), which dominate high star formation rate (SFR) density at z~1, in the sample identified by cross-correlating with the Spitzer/MIPS 24um source catalog. We perform two-dimensional light profile fitting of the z~1 galaxies in the Ks-band (rest-frame J-band) with a single component Sersic model. We find that at z~1, ~90% of LIRGs have low Sersic indices (n<2.5, similar to disk-like galaxies) in the Ks-band, and those disk-like LIRGs consist of ~60% of the whole disk-like sample above M_{s} >= 3 x 10^{10} M_{sun}. The z~1 disk-like LIRGs are comparable or ~20% small at a maximum in size compared to local disk-like galaxies in the same stellar mass range. If we examine rest-frame UV-optical morphologies using the HST/ACS images, the rest-frame B-band sizes of the z~1 disk-like galaxies are comparable to those of the local disk-like galaxies as reported by previous studies on size evolution of disk-like galaxies in the rest-frame optical band. Measuring color gradients (galaxy sizes as a function of wavelength) of the z~1 and local disk-like galaxies, we find that the z~1 disk-like galaxies have 3-5 times steeper color gradient than the local ones. Our results indicate that (i) more than a half of relatively massive disk-like galaxies at z~1 are in violent star formation epochs observed as LIRGs, and also (ii) most of those LIRGs are constructing their fundamental disk structure vigorously. The high SFR density in the universe at z~1 may be dominated by such star formation in disk region in massive galaxies.Comment: 16 pages, 15 figures, accepted for publication in PASJ. Catalog data will be available at http://astr.tohoku.ac.jp/MODS/wiki/index.php soo