Stem cell, experimental animals and cell culture studies in diabetes

This book aims to provide a current and comprehensive perspective on Diabetes mellitus, a valuable subject in the field of basic sciences. Diabetes mellitus is a chronic disease that affects millions of people worldwide and has become an increasingly serious health problem. This book examines the underlying mechanisms and causes of diabetes using the disciplines of basic sciences. The content of the book begins with fundamental information such as the definition, classification, histopathological mechanisms, and epidemiology of diabetes. It also includes interesting sections on current technologies and the use of artificial intelligence in the field of diabetes. Additionally, the book extensively discusses how genetic predisposition, environmental factors, and lifestyle choices affect the risk of diabetes. This comprehensive evaluation of diabetes from the perspective of basic sciences provides important insights into the development and progression of the disease

Effect of Moringa oleifera on serum YKL-40 level: In vivo rat periodontitis model

Periodontitis is a chronic inflammatory disease that destroys the bones and soft tissues that support the tooth as a result of inflammatory reactions. YKL-40 is an inflammatory marker associated with inflammation and is also associated with periodontal diseases. Moringa oleifera (MO) is a plant rich in high nutritional values, minerals, vitamins, and other essential phytochemicals. The aim of this study was to investigate the effect of MO administration on serum YKL-40 levels in an experimental periodontitis model. In the study, a total number of 24 female Wistar albino rats, which were 4–5 months old with a body weight of 275 ± 25 g, were used. Animals were divided into three groups. 1st group: Control (n = 8), 2nd group: periodontitis group (PG) (n = 8), 3rd group: Periodontitis group (PG + MO) with an additional 200 mg/kg/4 weeks MO (n = 8). In the PG and PG + MO were formed experimental periodontitis model. Compared to the PG, the decrease in the interleukin-6 (IL-6) and YKL-40 values in the PG + MO (p < 0.05, p < 0.05) was found to be significant in terms of statistical evaluation. As a result, MO decreased YKL-40 levels in the experimental periodontitis model. Although further research is needed, drugs containing MO can be used in the treatment of periodontal diseases

Current multidisciplinary approach to diabetes mellitus occurrence mechanism

This book aims to provide a current and comprehensive perspective on Diabetes mellitus, a valuable subject in the field of basic sciences. Diabetes mellitus is a chronic disease that affects millions of people worldwide and has become an increasingly serious health problem. This book examines the underlying mechanisms and causes of diabetes using the disciplines of basic sciences. The content of the book begins with fundamental information such as the definition, classification, histopathological mechanisms, and epidemiology of diabetes. It also includes interesting sections on current technologies and the use of artificial intelligence in the field of diabetes. Additionally, the book extensively discusses how genetic predisposition, environmental factors, and lifestyle choices affect the risk of diabetes. This comprehensive evaluation of diabetes from the perspective of basic sciences provides important insights into the development and progression of the disease

Current compherensive approach to Covid-19

This book, prepared by our Karamanoglu Mehmetbey and other faculty members by adding their current experiences during the pandemic process, is one of the leading scientific publications about the COVID-19 pandemic