Treatment of migraine in general practice

Migraine is a rather common disorder in general practice. The article discusses the problems of pathogenesis and diagnosis of migraine, including the severe forms of the disease and its' different masks. The paper contains the data on the current approach to curing acute attacks and preventive treatment of migraine in general practice

Disturbances of early embryogenesis in high-productive dairy cows

The article presents research materials to identify signs of the manifestation of early embryogenesis-developmental delay syndrome and intrauterine flexibility in dairy cows. The syndrome of delayed development of the embryo and fetus is recorded in 33.0% of fertilized cows, and intrauterine flexibility in 16.5%, including with productivity of 4, 000-5, 000 kg, respectively, at 26.9% and 11.9%, with productivity of 6, 000-7, 000 kg at 33.2% and 16.8%, and with productivity of 8, 000-9, 000 kg at 38.9% and 20.0%. Developmental syndrome and prenatal flexibility are most often diagnosed in first-lactation cows (45.5% and 25.4%) and have a tendency to lower the age of animals, as well as in animals fertilized after four or more insemination-47.6% and 30.8%, which is, respectively, 1.96 and 3.58 times more compared to cows which were pregnant after the first insemination. There is a tendency to reduce the size of the corpus luteum in the first 3 weeks of pregnancy, even during the physiological course, including within 5-6 days-by 14.7%-23.7%, 10-12 days-by 6.7%-11.6%, and 1923 days - by 4.8-7.7%. Factors indicating malnutrition of the developing embryo and fetus. During the physiological course of pregnancy, in 38-45 days, the embryo’s length is longer compared to cows with delay syndrome and prenatal flexibility, respectively, 1.66 and 3.19 times, body diameter - 1.53 and 3.18 times, 60-65 days, it was, respectively, 1.85 and 1.4 times. The size of the fetus in highly productive cows is smaller than in animals with lower milk productivity-by 4.6%-7.7% and 9.4%-23.0%. Compared with animals suffering from the embryo and fetal growth retardation, progesterone levels increase by 8.5%-33.8%. Pregnancy in highly productive cows occurs against the background of low progesterone levels, which is a risk. In high-yielding cows, progesterone levels, even with the physiological course of pregnancy, are lower than those of low-producing animals by 16.9%-25.3%. © 2020, Advanced Scientific Research. All rights reserved