A new cyano-substituted fluorescamine superior to its original form as a fluorescent probe for amino acid detection

Available online 7 February 2018.Synthesis and spectral study of two new cyano-substituted fluorescamine as the fluorescent probes for amino acid detection have been carried out comparing with the original fluorescamine. Of the three compounds, the derivative with a cyano group at the meta-position on the 4-phenyl group was found to be superior to the original one in the reactivity toward some amino acids as well as the fluorescence intensity of the adducts. The fluorescent amino acid adducts were also applied to the peroxyoxalate chemiluminescence system as the fluorophores, in which the derivative described above was found to be more effective also in chemiluminescence than the original one. (C) 2018 Elsevier Ltd. All rights reserved.ArticleTETRAHEDRON LETTERS. 59(12):1104-1107 (2018)journal articl

Increasing Incidence and Age at Onset of Amyotrophic Lateral Sclerosis in Nagano Prefecture, Japan

Article信州医学雑誌 64(5): 239-246(2016)journal articl

Distribution of dust clouds around the central engine of NGC 1068

We studied the distribution of dust clouds around the central engine of NGC 1068 based on shifted-and-added 8.8 - 12.3 micron (MIR) multi-filter images and 3.0 - 3.9 micron (L-band) spectra obtained with the Subaru Telescope. In a region of 100 pc (1.4") around the central peak, we successfully constructed maps of color temperatures and emissivities of the MIR and L-band continua as well as the 9.7 micron and 3.4 micron dust features with spatial resolutions of 26 pc (0.37") in the MIR and 22 pc (0.3") in the L-band. Our main results are: 1) color temperature of the MIR continuum scatters around the thermal equilibrium temperature with the central engine as the heat source while that of the L-band continuum is higher and independent upon distance from the central engine; 2) the peak of the 9.7 micron silicate absorption feature is shifted to a longer wavelength at some locations; 3) the ratio of the optical depths of the dust features is different from the Galactic values and show complicated spatial distribution; and 4) there is a pie shaped warm dust cloud as an enhancement in the emissivity of the MIR continuum extending about 50 pc to the north from the central engine. We speculate that material falls into the central engine through this cloud.Comment: 26 pages, 9 figures. Accepted for publication on Ap