122,442 research outputs found
A note on spacelike and timelike compactness
When studying the causal propagation of a field in a globally hyperbolic
spacetime M, one often wants to express the physical intuition that it has
compact support in spacelike directions, or that its support is a spacelike
compact set. We compare a number of logically distinct formulations of this
idea, and of the complementary idea of timelike compactness, and we clarify
their interrelations. E.g., a closed subset A of M has a compact intersection
with all Cauchy surfaces if and only if A is contained in J(K) for some compact
set K. (However, it does not suffice to consider only those Cauchy surfaces
that partake in a given foliation of M.) Similarly, a closed subset A of M is
contained in a region between two Cauchy surfaces if and only if the
intersection of A with J(K) is compact for all compact K. We also treat future
and past compact sets in a similar way
Effects of flavor conserving CP violating phases in SUSY models
I summarize our recent works on the effects of flavor conserving CP violating
phases in SUSY models on and phenomenology.Comment: Contributed alk at the 3rd International Conference on B Physics and
CP Violation (BCONF99), Taipei, Taiwan, 3-7 Dec 1999 (4 pages
Prevention of venous thromboembolism after hip and knee replacement among older adults
BACKGROUND: Venous thromboembolism (VTE) after total hip and knee replacement is a major patient safety threat, and pharmacologic prophylaxis is generally recommended. However, clinicians disagree on the optimal prophylaxis agent.
OBJECTIVE: We sought to compare effectiveness and safety of aspirin versus anticoagulants for VTE prophylaxis after hip and knee replacement.
METHODS: We identified patients aged ≥ 65 years undergoing elective hip and knee replacement during 2011–2013 in 59 hospitals nationwide and included in the Institute for Health Metrics clinical database. We limited our analysis to the patients with electronic medical record of discharge prophylaxis medication. Patients were categorized into either anticoagulant or aspirin only group. VTE, major hemorrhage, cardiovascular event, and death were identified from electronic databases and validated by physician review of the source documents. We compared the 90-day risk of VTE and the composite outcome (VTE, cardiovascular events, major hemorrhage, and death) in the anticoagulant group to the aspirin group using Cox proportional hazards analysis.
RESULTS: Study sample included 5648 patients with mean age 73 years. The overall number of outcome events was low. There were 35 VTE events (0.61%), 15 (0.26%) cardiovascular events, 17 major hemorrhages (0.30%), and 18 deaths (0.31%). In multivariable analysis adjusting for patient demographics and cardiovascular disease and risk factors, anticoagulation therapy was associated with decreased risk of VTE (HR 0.76, 95% CI 0.35–1.68) and the composite outcome (HR 0.80, 95% CI 0.48–1.32) although not statistically significant.
CONCLUSION: Among older adults undergoing elective total hip and knee replacement in community hospitals, the 90-day risk of VTE and the composite outcome was low. We did not find any statistical difference in the risk of the outcomes between anticoagulation and aspirin. Future studies with a larger sample size and different patient population are needed to validate our results.2019-11-08T00:00:00
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