The Level Assessment of Extracellular Nucleic Acids in the Blood of Pregnant Women with Chronic Hypertension with Superimposed Preeclampsia

BACKGROUND: Preeclampsia, chronic arterial hypertension is one of the causes of maternal and perinatal morbidity and mortality. AIM: The aim of our study was to assess the level of extracellular nucleic acids in red blood cells and blood plasma in pregnant women with severe preeclampsia, severe chronic hypertension, and pregnant women with chronic hypertension with superimposed preeclampsia. METHODS: A total of 107 pregnant women were examined who were hospitalized at the Regional Clinical Hospital and at the Regional Perinatal Center in Karaganda and 29 healthy non-pregnant women. Pregnant women were divided into four groups: 1 group – 32 pregnant with severe chronic hypertension, 2 group – 48 pregnant women with severe preeclampsia, 3 group – 35 women entered the group with chronic hypertension with superimposed preeclampsia, and group control – 29 healthy non-pregnant women of child bearing age (4th group – control). RESULTS: The content of ecNA in the erythrocytes of pregnant women with chronic hypertension with superimposed preeclampsia sharply increases relative to the control and comparison groups; in pregnant women with severe hypertension and severe preeclampsia, the level of ecNA is moderately higher relative to the control, but lower than in the main group. CONCLUSION: Our data indicate significant changes in the level of ecNA in pregnant women with various types of hypertension and require further research, but now, changes in the concentration of ecNA can be considered as one of the links in the pathogenesis of preeclampsia

Mathematical Modeling of Multi-Element Antenna Arrays with Chiral Metamaterials Substrates Using Singular Integral Equations

In this paper, a physical model of the multi-element antenna arrays (MEAA) has been considered and a self-consistent numerical method for solving the problem of current distribution on the MEAA surface with chiral metamaterials substrate has been proposed. The algorithm of the input admittance matrix elements for chiral layer based on the conductive left and right-handed helices has been developed and elements of the matrix surface impedances for investigated structures have been found. A set of singular integral equations with a Cauchy kernel for calculating the current density on the surface of the MEAA has been derived. A numerical solution of the set is a well-posed in the sense of Hadamard. Calculations of current distribution on the MEAA surface, impedance characteristics of a three-element antenna array and the dependence of the isolation levels between emitters on the chirality parameter have been performed and analysed. It has been shown that the use of chiral substrates can substantially increase the isolation between emitters

Mathematical Modeling of Multi-Element Antenna Arrays with Chiral Metamaterials Substrates Using Singular Integral Equations

In this paper, a physical model of the multi-element antenna arrays (MEAA) has been considered and a self-consistent numerical method for solving the problem of current distribution on the MEAA surface with chiral metamaterials substrate has been proposed. The algorithm of the input admittance matrix elements for chiral layer based on the conductive left and right-handed helices has been developed and elements of the matrix surface impedances for investigated structures have been found. A set of singular integral equations with a Cauchy kernel for calculating the current density on the surface of the MEAA has been derived. A numerical solution of the set is a well-posed in the sense of Hadamard. Calculations of current distribution on the MEAA surface, impedance characteristics of a three-element antenna array and the dependence of the isolation levels between emitters on the chirality parameter have been performed and analysed. It has been shown that the use of chiral substrates can substantially increase the isolation between emitters