Angiotensin-converting enzyme gene insertion/deletion polymorphism and renal disease

The present thesis aims to provide new data concerning the impact of the ACE I/D polymorphism on the progression of renal disease and the effect of renoprotective therapy. We will especially put emphasis on the presently underemphasized role of gene-environment interactions. Directions will be given to help the reader to interpret present and future studies on this subject and to provide suggestions for further studies that are needed in the future.