95 research outputs found
Small Cofactors May Assist Protein Emergence from RNA World: Clues from RNA-Protein Complexes
It is now widely accepted that at an early stage in the evolution of life an RNA world arose, in which RNAs both served as the genetic material and catalyzed diverse biochemical reactions. Then, proteins have gradually replaced RNAs because of their superior catalytic properties in catalysis over time. Therefore, it is important to investigate how primitive functional proteins emerged from RNA world, which can shed light on the evolutionary pathway of life from RNA world to the modern world. In this work, we proposed that the emergence of most primitive functional proteins are assisted by the early primitive nucleotide cofactors, while only a minority are induced directly by RNAs based on the analysis of RNA-protein complexes. Furthermore, the present findings have significant implication for exploring the composition of primitive RNA, i.e., adenine base as principal building blocks
Optically active heteroligand chelate complexes. 5. Heteroligand chelates of nickel with acetylacetone and aromatic amino acids
Asymmetric synthesis of amino acids by catalytic reduction of azalactones of substituted acylaminoaceylic acids
Optically active alkoxy- and alkylchlorosilanes as starting compounds for the preparation of stereospecific silica gels and silicon-containing polymers
Asymmetric synthesis of amino acids by means of catalytic reduction of azlactones of substituted acylaminoacrylic acids Communication 14. Influence of the nature of the solvent on reductive ammonolysis of ?2-oxazol-5-ones
Adsorption of the racemic mixture and the (+) isomer of butanol-2 on stereospecific silica gel
Synthesis of optically active methylmenthoxychlorosilanes and menthyl esters of methylchlorosilylpropionic and methylchlorosilylisobutyric acids
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