133 research outputs found
Altered Hemodynamics Associated with Pathogenesis of the Vertebral Artery Dissecting Aneurysms
The etiology of the vertebral dissecting aneurysms is largely unknown, and they frequently occurs in relatively healthy young men. Objectives and Methods. A series of 57 consecutive cases defined by angiography were evaluated with regard to deviation in the course of the affected and contralateral vertebral arteries. Division was into 3 types: Type I without any deviation, Type II with mild-to-moderate deviation but not over the midline; and Type III with marked deviation over to the contralateral side beyond the midline. Results. The most frequent type of VA running was Type III for the affected and Type I nonaffected side, with this being found in all 17 patients except one. All of the Type III dissections occurred just proximal to a tortuous portion, while in cases with Type-I- and Type-II-affected sides, the majority (33 of 39) occurred near the union of the vertebral artery. In 10 of 57, a non-dominant side was affected, all except one being of Type I or II. With 12 recent patients assessed angiographically in detail for hemodynamics, eleven patients showed contrast material retrograde inflowing into the pseudolumen from the distal portion of the dissection site. Turbulent blood flow was recognized in all of these patients with retrograde inflow. Conclusions. Turbulent blood flow is one etiology of vertebral artery dissection aneurysms, with the sites in the majority of the cases being just proximal to a tortuous portion or union of vessels. In cases with dissection proximal to the tortuous course of the vertebral artery, retrograde inflow will occur more frequently than antegrade, which should be taken into account in designing therapeutic strategies
Putting “sticky notes” on the electronic medical record to promote intra-hospital referral of hepatitis B and C virus-positive patients to hepatology specialists: an exploratory study
Case Report - Postoperative reversible deterioration in a spinal dural arteriovenous fistula
This 61-year-old man presented with weakness and sensory disturbance in
the legs. There was a spinal dural arteriovenous fistula (SDAVF) fed by
the left sixth intercostal artery with dorsal perimedullary drainage.
Surgical division of the perimedullary drainage led to rapid
neurological improvement. However, on the second postoperative day he
experienced transient deterioration of second neuron function in the
left upper lumbar segment resulting in motor weakness of the proximal
leg muscles, absence of the patellar deep tendon reflex and thigh pain.
No radiological findings explaining this deterioration were obtained.
He was treated conservatively and all segmental symptoms and signs
subsided by the fifth postoperative day. Although the precise
mechanisms underlying the dramatic but often reversible deterioration
after radical SDAVF treatment remain to be determined, we postulate
that this was attributable to postoperative segmental venous
hemodynamic changes based on the neurological changes
Usefulness of gamma knife pituitary surgery to control thalamic pain after treatment of thalamic malignant lymphoma and report of pathology of gamma knife lesions
Here, we describe the first reported autopsy findings following gamma
knife surgery for thalamic pain. A 62-year-old man presented with
thalamic pain after treatment for thalamic malignant lymphoma. He was
treated with narcotic drugs, but his pain was uncontrollable. Treatment
using gamma knife surgery on the pituitary gland using a maximum dose
of 180 Gy, led to the control of his intractable pain with lower doses
of drugs. His death was pain-free and was caused by a recurrence of the
tumor, six months after gamma knife surgery. An autopsy was performed
and necrosis was present in the area of the pituitary gland where it
borders the pituitary stalk. Half of the adenohypophysis was not
necrotic, and necrosis was not found in the pituitary stalk
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